Diabetic Foot

The diabetic foot is prone to complications, as clearly indicated by the high number of hospital admissions amongst individuals with diabetes due to foot problems. What may seem like a ‘simple’ foot ulcer can easily lead to an amputation. Sadly, a leg is amputated every 30 seconds, with up to 70% of all leg amputations happening to individuals with diabetes. Yet up to 85% of amputations can be avoided with preventative measures and adequate care.

diabetic foot conditions assessment
Retrieved from https://www.medicostuff.com/category/medicine/diabetes-mellitus/ on 26th March 2022
Retrieved from https://www.diabetesfeetaustralia.org/welcome-world-diabetes-day/ on 2nd July 2022
Retrieved from https://www.diabetesfeetaustralia.org/diabetic-foot-disease-is-a-top-10-cause-of-global-disability/ on 2nd July 2022

Diabetic Foot Ulcers – Treat as an Aggressive Cancer!

Diabetic foot complications, including amputations, can be avoided by:

  1. applying a preventative approach through cost-effective strategies
  2. identifying high risk individuals and providing them with related health literacy eg. to check their feet daily, dry them thoroughly, and wear appropriate footwear
  3. knowing when a diabetic foot ulcer has become a complicated lesion: ischaemia and infection
  4. knowing which and when to apply a proper off-loading device
  5. providing continuity in treatment and management between hospital and the community, along with organisation and communication between both settings

However…

  • 5% of individuals with new ulcers die within 12 months following their first physician visit regarding a foot ulcer
  • 42.2% of individuals with foot ulcers die within 5 years
  • 70% of diabetic foot ulcers recur over the following 3 years

“When people with diabetic foot ulcers heal, just like with cancer, they are not really healed. Our patients are in remission. We tend to think about wounds when they are open but why don’t we think about them when they are closed?

We should be aiming for having people at home in diabetic foot remission monitoring themselves”

Armstrong, Boulton and Bus, 2017.
Retrieved from https://www.sciencedirect.com/science/article/abs/pii/S1067251607600015 on 2nd July 2022

Diabetic Foot Lesions Risk Factors

Retrieved from https://www.wjgnet.com/1948-9358/figures/v6/i1/37.htm on 2nd July 2022
Retrieved from https://www.researchgate.net/publication/242514797_DIABETIC_FOOT_DISORDERS/figures?lo=1 on 2nd July 2022

Routine Diabetic Foot Screening

1. COLLECT MEDICAL HISTORY

  • ask regarding any previous foot ulcers or lower extremity amputations
  • assess regarding poor access to healthcare and financial constraints
  • ask if patient is experiencing foot issues eg. foot pain (walking or resting), numbness, claudication (pain whilst walking or using arms – may be a symptom of peripheral artery disease)
  • ask if patient is experiencing dyspnoea
  • ask if patient has end stage renal disease

2. INSPECT & ASSESS FOOT

  • assess skin colour, temperature, and for callus or oedema presence
  • assess for lesions such as pre-ulcerative signs, active ulcers, fissures, cracks and blisters
  • check for bone and joint deformities eg. claw or hammer toes, abnormal large bony prominences, or limited joint mobility
  • check if patient is using ill-fitting or inadequate footwear
  • inspect patient feet for poor feet hygiene eg. improperly cut toenails, unwashed feet, superficial fungal infections, or unclean socks
  • notice any patient physical limitations that may hinder proper foot care eg. obesity, visual impairment, etc.
  • question patient on foot care health literacy – see what patient education is required for better self-care

3. ASCERTAIN PATIENT UNDERSTANDING & EDUCATION

  • explain the screening process and the rationale behind it
  • provide reassurance in case of anxiety
  • provide patient education, counseling and support whilst screening the patient’s feet
  • following screening, provide results to the patient, including any risks for foot problems, both in verbal and written form, along with contact details in case of any future questions

Peripheral Arterial Disease

Peripheral arterial disease is the main cause of delayed healing in the diabetic foot, associated with neuropathy in about 80% of all cases:

  • macroangiopathy – similar to atherosclerosis, but is distributed in the distal segments of the lower extremities i.e. the calf and foot arteries
  • arterial calcification – ‘hardening of the arteries’ – calcium forms hard crystals in the blood vessel walls
  • microangiopathy – thickening of the capillary basement membrane which compromises gaseous exchange

Assessing Dorsalis Pedis & Posterior Tibial Pedal Pulses

  • absence of both pedal pulses on one foot strongly suggests pedal vascular disease
  • if no pulse can be located, refer patient to a vascular specialist or a relevant health professional for further assessment

NOTE: further examinations which need to be performed by a trained healthcare professional include the Ankle Brachial Pressure Index (ABPI), Systolic Toe Blood Pressure (STBP), and the Toe Brachial Pressure Index (TBPI)

Retrieved from https://journals.rcni.com/nursing-standard/leg-ulceration-part-2-patient-assessment-ns2004.09.19.2.45.c3699 on 2nd July 2022

Diabetic Neuropathy

Up to 70% of individuals with diabetes have mild to severe forms of nervous system damage. This includes:

  • impaired sensation or pain in extremities
  • slow food digestion in the stomach
  • carpal tunnel syndrome
  • other nerve issues

With diabetic peripheral neuropathy, one may not be able to feel:

  • temperature changes
  • pressure
  • pain
  • vibration

NOTE: individual with peripheral neuropathy may also experience painful sensory neuropathy which includes burning and tingling sensations a.k.a. paresthesia.

The Motor Neuropathic Diabetic Foot

Neuropathic foot features include:

  • predominant neuropathy
  • adequate circulation
  • palpable pulses
  • warm, dry, and often painless

Complications include:

  • muscle weakness
  • muscle twitching
  • muscle paralysis
  • neuropathic ulcer commonly found at the sole of the foot
  • charcot foot
  • neuropathic oedema

Neuropathic Ulcer

Charcot Foot

Charcot foot is a condition that causes bones in the foot to weaken, leading to fractures and shape changing. This typically occurs in individuals with neuropathy.

Retrieved from https://peninsulapod.com/charcot-foot/ on 26th March 2022

Neuropathic Oedema

The Neuro-Ischaemic Diabetic Foot

Neuro-Ischaemic foot features include:

  • neuropathy
  • absent foot pulses
  • feels cool to touch
  • thin, shiny, hairless skin
  • subcutaneous tissue atrophy
  • increased pain at rest (may be absent due to neuropathy)
diabetic foot conditions assessment
Left: Neuropathic foot with prominent metatarsal heads and pressure points over the plantar forefoot. Right: Neuroischaemic foot showing pitting oedema secondary to cardiac failure, and hallux valgus and erythema from pressure from tight shoe on medial aspect of first metatarsophalangeal joint – Retrieved from https://europepmc.org/article/med/16484268 on 26th March 2022

The Ischaemic Diabetic Foot

Ischaemic foot features include:

  • peripheral vascular disease
  • absent signs of peripheral neuropathy
  • cold, shiny, hairless skin
  • rare in diabetic patients
diabetic foot conditions assessment
Retrieved from https://en.wikipedia.org/wiki/Ischemia on 26th March 2022

Diabetic Foot Assessment

To perform a diabetic foot assessment, shoes, socks, and any would dressings from both feet should be removed. This should be followed by a thorough examination for evidence of the following risk factors:

  • ulcers
  • callus
  • gangrene
  • deformity
  • infection
  • inflammation
  • charcot foot
  • limb ischaemia
  • neuropathy

Wound Assessment and Description

Retrieved from https://slideplayer.com/slide/12696492/ on 27th March 2022
Retrieved from https://www.researchgate.net/publication/311988179_Triangle_of_Wound_Assessment_Made_Easy_Revisited/figures on 27th March 2022

Assessing Sensation with a tuning fork

Assessing for Neuropathy using 10g Monofilament

Assessing for Vascular Problems

  1. Is lower limb blood supply adequate for normal function and tissue viability?
  2. Can you identify any arterial or venous vascular problems which may compromise the current state of the tissues?
  3. Are there any vascular abnormalities that may affect the patient’s healing or treatment options?
  4. What can you do to avoid possible complications?
  5. Does the patient have a vascular condition that requires further investigations by a specialist?

Calculating Ankle-brachial index

Retrieved from https://www.researchgate.net/publication/233765986_Anklebrachial_index_to_everyone/figures?lo=1 on 27th March 2022

Osteomyelitis

Foot Ulcer Treatment – Key Elements

  1. providing local wound care
  2. providing pressure relief for ulcer protection
  3. providing infection treatment
  4. restoring skin perfusion
  5. preventing recurrence
  6. treating or controlling other comorbidities eg. diabetes
  7. providing related health literacy to patients and their relatives

Provide the patient with oral and written information in detail, including information about diabetes control, foot emergencies, and contact person details.

Offloading

Offloading promotes reduction, redistribution, or removal of detrimental forces applied to the foot. Offloading alleviates pressure at areas of high vertical and shear stress.

Foot plantar pressure is the pressure field which acts between the foot and the support surface during everyday activities. The main aim of offloading devices is to redistribute plantar pressures evenly, which helps avoid areas of high pressure that prevent or delay healing.

A, Total contact cast; B, Charcot Restraint Orthotic Walker boot; C, prefabricated walker; D, DH walker; E, IPOS shoe; F, OrthoWedge; G, postoperative shoe; H, healing sandal; I, reverse IPOS; J, L’nard splint; K, patella tendonbearing brace; L, MABAL shoe. 1, Dorsal digit; 2, plantar digit; 3, plantar metatarsal; 4, medial metatarsal; 5, lateral metatarsal; 6, heel.

Retrieved from https://www.researchgate.net/publication/269766812_The_Management_of_Diabetic_Foot_Ulcers_Through_Optimal_Off-Loading_Building_Consensus_Guidelines_and_Practical_Recommendations_to_Improve_Outcomes/figures?lo=1 on 3rd July 2022

References

Armstrong, D., Boulton, A., & Bus, S. (2017). Diabetic Foot Ulcers and Their Recurrence. The New England Journal of Medicine, 376(24), 2367-2375. Retrieved from http://81.143.226.227/Medicine/Papers/2017_06_15%20NEJM%20Diabetic%20Foot%20Ulcers%20and%20Their%20Recurrence.pdf on 2nd July 2022.


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Leg Ulcers Nursing Care

Leg ulcers can be defined as loss of skin in areas below the knee (on the leg or foot) which take longer than 6 weeks to heal.

  • venous disease (60-80% of all leg ulcers are of venous origin) – conditions that damage the veins eg. blood clots, deep vein thrombosis, phlebitis, varicose veins, spider veins, and chronic venous insufficiency.
  • arterial disease (10-30% of all leg ulcers are of arterial origin) – a.k.a. artery disease is a vascular disease affecting the body’s arteries.
leg ulcers
Retrieved from https://www.woundsource.com/blog/venous-vs-arterial-wounds-differential-diagnosis-and-interventions on 26th January 2022
  • diabetes mellitus – metabolic diseases characterised by hyperglycaemia due to problems with insulin secretion, insulin action, or both.
  • rheumatoid arthritis – an autoimmune inflammatory disease in which the immune system attacks the body’s healthy cells, leading to inflammation in the affected parts, most commonly the joints.
  • sickle cell anaemia – red blood cell disorder, usually inherited, in which there is lack of healthy red blood cells. In normal circumstances, red blood cells are flexible and round, thus can move easily through the blood vessels. In sickle cell anaemia, red blood cells are shaped like sickles or crescent moons.
Retrieve from https://www.sicklecellfoundation.com/leg-ulcer-in-sickle-cell-disorder/ on 6th November 2021
  • lymphoedema – a chronic condition that causes the body’s tissues to swell, most commonly affecting the arms or legs as a result of an inefficient lymphatic system.
Retrieved from https://woundeducators.com/lymphedema-overview-and-etiology/ on 6th November 2021
  • tumors – abnormal mass of tissue resulting from excessive cell division or cells that do not die when they should.
Retrieved from https://www.actasdermo.org/en-diagnostic-treatment-leg-ulcers-articulo-S1578219012000224 on 6th November 2021

Sustained Venous Hypertension

Sustained Venous Hypertension happens when valves are damaged, leading to increased blood pressure in the leg veins, possibly causing ulcer formation. Sustained Venous Hypertension is caused by:

  • Superficial Venous Incompetence – a common condition occurring due to decreased blood flow from the leg veins up to the heart. Lack of adequate blood flow results in blood pooling in the leg veins, leading to conditions such as spider veins, reticular veins and varicose veins.
  • Deep Venous Incompetence – a problem with the valves of the veins of the legs, blockage of the veins, or both, leading to leg ulcers, pain and swelling.
  • Deep Venous Obstruction – partial or complete occlusion of the lumen leading to decreased blood flow and increased blood pooling (frequently mistaken as DVT – diagnosis requires ultrasound investigation).
  • Previous Deep Vein Thrombosis – a medical condition resulting from blood clot formation within a deep vein.
  • Impaired Calf Muscle Pump Function – issues related to vein patency, valve competence, and proper calf muscle function.
  • Immobility – lack of ability to move freely
  • Joint Disease – a common wear and tear disease typically caused by repetitive motions resulting in inflammation and structural joint damage, leading to pain, redness and swelling.
  • Paralysis – loss of muscle function resulting from issues with the way messages are passed from the brain to the muscles. Paralysis can be complete or partial, on one or two sides of the body, in one area or widespread.
  • Obesity – a complex disease involving excessive amounts of body fat, possibly leading to immobility, femoral vein compression, and high abdominal pressures.
  • Congestive Cardiac Failureheart disease which is caused by the cardiac muscle pumping blood in a less efficient manner than it should.

Chronic Venous Insufficiency

Rare Causes Of Leg Ulcers

Pyoderma Gangrenosum

Vasculitis

Factors Associated With Venous Ulcers VS Arterial Ulcers

VENOUS ULCERS

  • eczema
  • skin staining
  • ankle flare
  • varicose veins
  • oedema
  • leg fracture
  • previous deep vein thrombosis
  • history of pulmonary embolism
  • history of varicose vein surgery

ARTERIAL ULCERS

  • intermittent claudication
  • diabetes
  • rheumatoid arthritis
  • previous arterial surgery
  • non-palpable foot pulses
  • shiny hairless skin
  • poor capillary refill
  • cold bluish foot
  • white colourless leg
  • history of heart disease
  • history of stroke or transient ischaemic attack

NOTE: patients who complain of not being able to walk for a while without resting, or needing to get out of bed at night to sleep on an armchair sitting down due to pain most probably have arterial ulcers.

Leg Ulcers Assessment and Management

Assessing the patient accurately leads to an accurate diagnosis. This is crucial for leg ulcers healing since different medical supplies are used for different diagnosis.

Investigating a leg ulcer should start by questioning its history – how long has it been there? Is there a pedal pulse present? Absent pedal pulse may indicate arterial deficiency.

A doppler ultrasound, which works like a blood pressure pump, allows correct diagnosis of arterial disease if present.

Graduated external compression is an important factor resulting in the treatment of venous leg ulcers, since such treatment overcomes the effects of venous hypertension by reducing venous stasis and preventing oedema. Compression treatment provides external pressure that counteracts the hydrostatic pressure within the veins whilst standing. The external pressure that compression treatment provides depends on the affected limb’s size and shape, the technique used, and the used product’s characteristics.

Ideally, a compression level of 40 mmHg at the ankle area is recommended to overcome venous hypertension.

Compression therapy should NOT be used for arterial disease!!

Studies have shown that designer dressing materials have no additional effect on wound healing than the healing achieved by the use of simple low adherent dressings covered with multilayer compression bandaging. Commonly used dressings include Aquacel Ag (absorbs and controls exudate), Inadine, and silicone-impregnated dressings.

NOTE: Avoid compression bandaging bony prominences as doing so can easily lead to pressure ulcer formation.

Other Therapies & Management

Total Negative Pressure

Maggot Therapy

Schlerotherapy

Stockings – for long term management

Barriers To Leg Ulcers Healing

  • dry wound bed
  • wet / highly exuding wound
  • slough presence
  • infection
  • poor nutrition
  • anaemia / poor blood supply
  • venous hypertension

Leg Ulcers Patient Education

Educate the patient with leg ulcers about:

  • the disease
  • recurrence and management of leg ulcers
  • the importance of exercise
  • the effect of obesity on leg ulceration
  • how better nutrition promotes better wound healing
  • leg elevation
  • mobility and its relevance to leg ulcer formation
  • skin care, including dry skin care to prevent further skin tissue damage
  • available treatments
  • when to seek help

NOTE: Patient should be warned that while changes in relation to the above may reduce the probability of leg ulcers to reappear, it may still happen.

Leg Ulcers Nursing Care

  1. Take detailed history
  2. Assess wound thoroughly and document all findings
  3. Make sure the patient receives a correct diagnosis
  4. Use appropriate dressings and correct compression bandaging
  5. In case of infection, liaise with medical professionals for possible additional treatment
  6. Topical antibiotic treatment should be avoided especially due to the problematic antibiotic resistance frequently encountered
  7. Consider relevant therapies in relation to the patient’s individual needs
  8. Identify patients in need of medical review
  9. Refer to specialist professionals if needed in a timely manner
  10. Be aware of the patient’s psychosocial impact of the wound
  11. Educate patient

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