Here you can find videos related to anti hyperlipidaemic drugs covered within cardiovascular pharmacology that help lower LDL cholesterol…
Cardiovascular pharmacology deals with the study of the effects of drugs upon the heart or circulatory system. Cardiovascular medicines help to prevent and treat cardiovascular disease, slow the progression of it as well as treat its symptoms whilst providing a better quality of life and increasing life expectancy.
Types of Cardiovascular Drugs include:
- Anti-Hypertensive Drugs
- Anti-Angina Drugs
- Anti-Arrhythmic Drugs
- Anti-Coagulants
- Anti-Hyperlipidaemic Drugs
Below you can find a collection of videos that can help provide a more visual approach to cardiovascular pharmacology, specifically on the AntiHyperlipidaemic Drugs.
Anti Hyperlipidaemic Drugs include:
HMG-CoA Inhibitors – Simvastatin, Atrovastatin and Rosuvastatin
- Lower elevated LCD Cholesterol.
- Causes a large reduction in coronary events and death from heart disease.
- Considered as 1st line treatment for patients with elevated coronary artery syndromes and ischaemic heart disease.
- Simvastatin is highly effective at night; others may be taken during the day as well.
- ADVERSE EFFECTS: liver damage, myopathy, rhambdomyolysis.
- CONTRAINDICATIONS: chronic liver disease, pregnancy and lactation.
- MONITOR: liver function tests (4-6wks initially, then yearly); muscle enzyme levels if patient complains of muscle pain.
Lipoprotein Lipase Activators – Fenofibrate, Gemfibrozil, Clofibrate and Bezofibrate
- Lowers serum TGs and increase HDL cholesterol levels.
- ADVERSE EFFECTS: GI disturbances, gall stone formation, myositis, myopathy and rhambdomyolysis.
Bile Acid Sequestrans
- Sequestrants bind to bile acids in the intestine, preventing them from being reabsorbed into the blood.
- SIDE EFFECTS: constipation, diarrhoea, bloating, flatulence.
- PATIENT EDUCATION: take before a meal or at bedtime. Leave at least 1 hour before or 4 hours after taking cholestyramine since it interferes with their absorption.
Hyperlipidaemic Drugs
HMG-CoA Inhibitors a.k.a. Statins
Special thanks to the creators of the featured videos on this post, specifically Youtube Channels Speed Pharmacology and Registered Nurse RN
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