Introduction to Medical Statistics

Statistics VS Medical Statistics

Statistics are quantities or sets of quantities which one can calculate from observed data. Thus, unless they are ratios, statistics should be reported in units. Medical statistics is a subdiscipline of statistics. Medical statistics can assist researchers in answering healthcare-related challenging questions.

“It is the science of summarizing, collecting, presenting and interpreting data in medical practice, and using them to estimate the magnitude of associations and test hypotheses. It has a central role in medical investigations. It not only provides a way of organizing information on a wider and more formal basis than relying on the exchange of anecdotes and personal experience, but also takes into account the intrinsic variation inherent in most biological processes.”

Kirkwood, 2003.

Population VS Sample

In relation to statistics, the term population refers to a well defined group of subjects that a researcher chooses to investigate about a particular issue. The size of such a population may be known or unknown, but when the study population is too big to be investigated fully, sampling becomes needed.

A sample is a feasible number of subjects chosen to represent a population, thus, the sample involved in the study needs to be as representative as possible to the target population. This can be achieved by:

  • selecting an adequate sampling population
  • using randomly selected participants rather than convenience sampling

Simple Random Sampling

Simple random sampling is a sampling method in which all members of a population have an equal chance of being chosen to participate in the study sample.

Retrieved from https://www.shsu.edu/~mgt_ves/mgt481/lesson9/sld014.htm on 20th November 2022

Stratified Random Sampling

In stratified random sampling, the population is stratified into defining blocks eg. gender and age.

medical statistics
Retrieved from https://analyticssteps.com/blogs/stratified-random-sampling-everything-you-need-know on 20th November 2022

Weighted Sampling

In weighted random sampling the subjects are weighted and the probability of each item to be selected is determined by its relative weight. This allows the sample to be more representative of the population.

Retrieved from https://www.geopoll.com/blog/weighting-survey-data-raking-cell-weighting/ on 20th November 2022

Cluster Sampling

In cluster sampling, random groups of individuals are recruited for the study sample.

medical statistics
Retrieved from https://www.simplypsychology.org/cluster-sampling.html on 20th November 2022

Convenience Sampling a.k.a. Opportunity Sampling

In this type of sampling, no consideration is taken with regards to representation. Thus, all members of a population that a researcher can access have the opportunity to be recruited.

medical statistics
Retrieved from https://sites.google.com/site/glossary2019/c/convenience-sampling on 20th November 2022

Snowball Sampling

When recruiting members into a sample population becomes difficult, researchers revert to snowball sampling, where recruits are asked to suggest friends who may be willing to participate in the study.

medical statistics
Retrieved from https://www.simplypsychology.org/snowball-sampling.html on 20th November 2022

Sampling Used in Qualitative Studies

Sampling used in qualitative studies is usually either purposeful sampling or theoretical sampling:

  • PURPOSEFUL SAMPLING – the researcher seeks individuals who can provide the required data
  • THEORETICAL SAMPLING – the researcher uses a sampling method which, although similar to purposeful sampling, also includes changing and/or adapting the participants’ selection throughout the study based on results obtained from previous participants

NOTE: sample size does not matter in qualitative studies, since the aim is to acquire in-depth understanding of a phenomena.

Data Collection Variables in Medical Statistics

Variables are characteristics, numbers, or quantities which can be measured or counted. Some examples of variables include age, sex, blood pressure results, oxygen saturation levels etc.

Categorical Variables a.k.a. Qualitative Variables

Data collection in qualitative studies typically takes place during in-depth interviews such as one-to-one interviews or focus group interviews, and in some cases, non-structured observation may also be involved.

Categorical variables give qualitative information about the subject being investigated. Thus, possible responses in this variable are not numerical in nature, but instead are different categories related to the subject.

Categorical variables can also be divided into two:

  • Nominal Variable – a variable with a number of categories eg. occupation
  • Binary Variable – a variable with only two possible responses eg. yes or no

Continuous variables a.k.a. Quantitative Variables

Continuous variables give quantitative information about the subject in question. Thus, continuous variable responses can be any quantities within a set interval of values. Some examples would be age and BMI.

Data collection in quantitative studies may include:

  • readily available data such as data related to hospital activity, registers, prevalence and determinants
  • self-administered questionnaires which may include numerical scales
  • structured interviews through phone, electronic media, or face to face interviews, all of which allow an element of explanation and feedback between the researcher and the participant
  • structured observation which typically happen during observation schedules within a particular setting

Ordinal Variables a.k.a. Discrete Variables

Ordinal variables give limited quantitative information because responses achieved are numerically related to each other, yet have to be one within a limited number of values.

medical statistics
Retrieved from https://prinsli.com/categorical-variables/ on 20th November 2022

Data Analysis

Descriptive Statistics

Descriptive statistics feature a summary of data in a clear, concise and easy-to-understand way, usually through a numerical approach.

Inferential Statistics

Inferential statistics are statistics which, after being calculated from a sample, inferences are made on the original population using the same statistics.

medical statistics
Retrieved from https://www.z-table.com/z-score-table-blog/the-differences-between-descriptive-and-inferential-statistics on 20th November 2022

Reference

Kirkwood, Betty R. (2003). essential medical statistics. Blackwell Science, Inc., 350 Main Street, Malden, Massachusetts 02148โ€“5020, USA: Blackwell. ISBN978-0-86542-871-3.


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Literature Searching Strategies For Dissertation Writing

When searching through literature searching strategies for the purpose of writing your dissertation, you need to seek a good strategy which is both comprehensive and systematic. A systematic collection of observations from research subjects (such as demographic characteristics, physical characteristics, biological markers, behaviours, or feelings, emotions or views) aiming to create information about these subjects is otherwise referred to as research. This can be performed in the following order:

  1. Reflect on potential research areas or questions which are of interest to you
  2. Carry out simple searches, both on Google and in textbooks so as to obtain general knowledge on the subject of your interest
  3. Attempt to develop your research question; you may find the need to refine your question at a later stage or even restart your search from scratch to change your chosen subject
  4. Seek assistance by experts in the field of your interest and discuss related information sources
  5. Carry out advanced electronic research
  6. As part of the selection process, search manually through resulting key studies so as to confirm their relevance to your PICO question
  7. At this stage you should now have a clear idea of which relevant studies you can use for your own review
  8. Seek once again your chosen expert in the same field of study to confirm whether your refined idea is appropriate and relevant to the local scenario and clarify any related questions

Study Approaches and Designs

Every research study aims to answer a research question, which in itself determines the best approach and design to be used.

CHOOSING THE BEST DESIGN:

  • EXPERIMENTAL DESIGN – Randomised Control Trial (RCT)
  • OBSERVATIONAL DESIGNCross Sectional, Cohort, and Case Control Study

CHOOSING THE BEST APPROACH:

  • QUANTITATIVE APPROACH – emphasises on objective quantifiable measurements of attributes, aiming to generalise to a wider population; this approach involves theory testing and numerical data collection which can be analysed using statistical techniques
  • QUALITATIVE APPROACH – emphasises on subjective measures which may be varied or may change over time; this approach, which usually relies heavily on data interpretation, involves theory development, commonly including data in words and narratives such as perceptions and experiences aiming to understand or explain a typical behaviour.

NOTE: in qualitative research, rigor influences the validity of the produced results, which in turn determines how useful the evidence produced is, in terms of evidence based practice.

Literature Searching Strategies

Carrying out an Electronic Search

To carry out an electronic search you should search for articles within electronic databases which provide access to various electronic journals eg. International Journal of Nursing Studies and Journal of Nursing Education. Such journals include a number of publications a.k.a. articles.

The efficacy of an electronic search depends on how well your research question has been designed, how extensive was your search in relation to words and phrases used, the use of search tools such as Truncations and Boolean Operators, the use of good databases, and your review of literature search strategies until you are happy with your end results.

Choosing Search words and/or Phrases

A well designed research question should feature PICO elements…

Retrieved from https://libguides.cdu.edu.au/c.php?g=167917&p=3738712 on 19th November 2022

Search terms used can be in the form of single words or phrases. Phrases should be put in inverted commas. Always keep in mind that search engines provide you ONLY with articles containing the words you use in your searches.

Finding synonyms for each of the PICO components may be facilitated by:

  • brainstorming
  • thesaurus
  • MeSH browser
  • taking ideas from previously written related articles
  • using all word options including words containing hyphenations, alternative spelling and abbreviations

Additional Search Tools

Boolean Logic Operators

Use of Boolean Logic Operators AND, Or, and NOT:

  • AND combines words/phrases together so that both appear within one article found by a search.

Example: a search for โ€˜needles AND fearโ€™ will find only those articles that contain both the words needles and fear.

  • OR enables a selection of any one of a number of specified words in a list.

Example: behavioural OR behavioral

  • NOT excludes specific words so articles containing them will not be identified.

Example: โ€˜fear of needles NOT fear of hospitalsโ€™

Truncation

  • Truncation helps search all the variations of a word without writing them.

Example: Child* picks up child, children, childhood etc

Wildcard

  • Wildcard helps you identify alternative spellings of the same word easily.

Example 1: An?emia would pick up anaemia and anemia

Example 2: H?emoglobin would pick up haemoglobin and hemoglobin

Phrase Searching

  • Phrase searching through the use of inverted commas helps you pick up articles containing your chosen phrase only.

Example: โ€œpressure soresโ€ picks up the phrase as written and not where both words are used separately

Searching within a Database

When conducting an electronic search, you can use databases that facilitate your work. Universities tend to subscribe to a substantial number of databases which include a wide variety of articles across different fields of study. For students following a course at the University of Malta there are a good number of databases that students can use for their literature searching strategies.

After finding a database to search in:

  1. use limiters – eg. ticking peer reviewed articles increases the likelihood of finding articles which are of good quality
  2. choose date/s – ideally limit your search to the last 3 years; if no interesting articles come up, widen your search to the last 5 years or more if need be
  3. do not use ‘Full text’ as a limiter
  4. do not use unnecessary limiters
  5. combine keywords in your searches using Boolean Operators
  6. use other search tools as mentioned further above to help define your searches
  7. stop searching only when you have exhausted all possible literature searching strategies for relevant content

NOTE: Keep a record of ALL searches you apply, including implemented changes, as well as the results obtained with each of your searches!


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Acid Base Balance in a Patient’s Arterial Blood Gases ABGs

In a critical care setting, the main aim is always oxygen perfusion; perfusion = survival = healing. Acid Base Balance a.k.a. pH balance, is the level of acids and bases in the blood at which the human body functions at its best. A pH between 7.35 and 7.45 is considered to be an optimum pH level since it promotes good oxygen perfusion throughout the body.

A cell without oxygen can compensate with the help of anaerobic respiration. This however produces lactate a.k.a. lactic acid. Thus, anaerobic respiration can only provide compensation for a short period of time.

Physiological pH values in the human body: retrieved from https://www.researchgate.net/deref/https%3A%2F%2Fdoi.org%2F10.1080%2F17425255.2021.1951223 on 18th November 2022

In normal circumstances, the body aims to maintain a healthy balance between the acid and alkaline within. This process is mostly active thanks to the lungs and the kidneys, both of which play an important role in maintaining the body’s pH balance. This means however, that for individuals with compromised kidneys or lungs, compensating pH imbalance becomes even more difficult.

An acid is a substance which is chemically able to donate a hydrogen ion to another substance. Acids, which have a pH <7, are formed by free H+ ions and carry a positive electrical charge a.k.a. cations.

A base a.k.a. buffer is any substance which is chemically able to accept a hydrogen ion. Most bases are insoluble, however, ones that dissolve in water are also called alkali. Alkalis are formed by OH ions a.k.a. Hydroxyl ions. They have a pH of >7 and carry a negative electrical charge a.k.a. anions.

pH is the measure of H+ (hydrogen ion) concentration in water.

pH is controlled by the following active organs:

LUNGS: excrete carbon dioxide in the form of carbonic acid (H2CO3), and dissociates into H2O + CO2 for excretion.

KIDNEYS: control bicarbonate excretion; the kidneys can form ammonia which combines with acid products of protein metabolism for excretion.

PLASMA PROTEINS: able to bind both to free H+ and OH ions, preventing changes in the pH (fine-tuning pH levels that are still within their normal range i.e. between 7.35-7.45).

Bicarbonate and pH Balance

Normal Blood Gases Values

ArterialVenous
pH7.35-7.457.33-7.43
PO2 (Partial Pressure of Oxygen)80-100mmHg / 11-15KPa35-49mmHg / 4.5-6KPa
PCO2 (Partial Pressure of Carbon Dioxide)35-45mmHg / 4.5-6.1KPa41-51mmHg / 5-6.5KPa
SO2 (Oxygen Saturation)95-100%65-80%
HCO3 (Bicarbonate)22-26mmol/l24-28mmol/l
Base Excess-2 to 20 to 4

NOTE: In the UK, PaCO2 and PaO2 are normally measured in kPa (kilopascal) whereas in Malta they are usually measured in mmHg (millimetres of mercury). 1kPa = 7.5mmHg.

  • pH – acidity or alkalinity measurement based on the hydrogen ions present
  • PaO2 – partial pressure of oxygen which is dissolved in arterial blood
  • SO2 – arterial oxygen saturation
  • PCO2 – the amount of carbon dioxide dissolved in arterial blood
  • HCO3 – the amount of bicarbonate in the blood
  • Base Excess – the amount of excess or insufficient level of bicarbonate in the system
Interpreting Arterial Blood Gases
Retrieved from http://medcraveonline.com/JACCOA/JACCOA-05-00199.pdf on 26th May 2021
Interpreting Arterial Blood Gases
Retrieved from https://cardiopulmnaz.weebly.com/arterial-blood-gases-abgs.html on 26th May 2021

Restoring Acid-Base Balance Through Compensation

The human body naturally attempts to keep the pH within normal range by restoring acid-base balance through the opposite unaffected system. For example, if the respiratory system is affected, the metabolic system attempts to compensate so as to restore normal pH.

Respiratory Compensation happens 2-4 HOURS following an established metabolic process.

Metabolic Compensation happens 2-4 DAYS following an established metabolic process.

ABGs Interpretation Algorithm

Retrieved from https://www.yournursingtutor.com/wp-content/uploads/2018/08/ABG-Decision-Tree-Freebie.pdf on 18th November 2022

Acid Base Balance Disorders


Interpreting Arterial Blood Gases
acid base balance
acid base balance
CO2 builds up and reacts with the water in the blood, forming carbonic acid – Retrieved from https://healthjade.net/respiratory-acidosis/ on 26th May 2021

https://www.youtube.com/watch?v=X0VjnFKDNI0

respiratory alkalosis acid base balance
Body removing more CO2 than is being produced by the tissues – Retrieved from https://www.pinterest.com/pin/532761830894111979/ on 26th May 2021
metabolic acidosis acid base balance
Retrieved from https://www.pinterest.com/pin/427349452111640534/ on 26th May 2021
metabolic alkalosis acid base balance
Retrieved from https://healthjade.net/hyperchloremic-acidosis/ on 26th May 2021

ABGs Interpretation

acid base balance
acid base balance
Retrieved from https://nurseslabs.com/arterial-blood-gas-abgs-interpretation-guide/ on 26th May 2021

Partially vs Fully Compensated & Uncompensated Arterial Blood Gases

Further information

Arterial Blood Gases Blogpost – http://student-nurse-life.com/arterial-blood-gases-interpreting-abg/

Reference

Featured image retrieved from https://www.medistudents.com/osce-skills/arterial-blood-gases on 18th November 2022


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Diagnosed with Familial Mediterranean Fever during Nursing School

In the Summer of this year I got diagnosed with FMF, otherwise known as Familial Mediterranean Fever – a rare genetic disorder. It wasnโ€™t the news I was hoping for, but it was an explanation of all the symptoms I was experiencing.

I suffered from unexplained abdominal pains, chest pains, and fever, and more recently, headaches, joint pain and muscle pain. No one knew what was causing my symptoms. One hospital admission after another for months. Multiple doctors’ visits. Several tests and investigations. I knew something was wrong, but I didnโ€™t know what it was. It was even worse when people didnโ€™t believe me or take me seriously. But I fought. I fought for myself. I fought for a diagnosis. And finally, a genetic blood test revealed the diagnosis that explained all the pains I was experiencing.

I went through all this whilst training in nursing school. It was very hard for me to work and study whilst battling health issues myself. But this experience has also helped me a lot, both personally and professionally. I became stronger and more resilient, but also more empathetic and caring. I knew what it was like to experience pain so bad it affects your life, feeling like your body is falling apart but having no idea whatโ€™s causing all of it. But thanks to the support and help of my family, my close friends, and the University of Malta, I pulled through and Iโ€™m now in my final year of my studies and will soon graduate as a nurse.

I am writing this in honour of anyone currently battling any health issues, especially those living with a rare disease, be it Familial Mediterranean Fever or not. Itโ€™s not easy. There are good and bad days. But do not let the disease define who you are or stop you from doing whatever it is you love doing. Because one thing it cannot take away from you is passion and determination to achieve your dream.

Anyone who also suffers from Familial Mediterranean Fever and would like to get in contact, please feel free to contact me on my FB account by clicking the FB icon in my Author’s Box below ๐Ÿ™‚


Would you like to be a guest writer for Student Nurse Life? Iโ€™d love to hear from you! Contact me ๐Ÿ™‚

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Tracheostomy Nursing Care in the Critical Care Setting

Tracheostomy is a procedure in which an artificial opening a.k.a. stoma is created at the level of the second or third cartilaginous ring from where the tracheo-bronchial tree is accessed and a tracheostomy tube is inserted. Proper tracheostomy nursing care in the critical care setting ensures patient safety.

Retrieved from https://entokey.com/laryngeal-anatomy/ (left) and https://www.pinterest.com/pin/83387030589729256/ (right) on 1st November 2022

Tracheostomy indications

  • airway obstruction in relation to problems with tongue, pharynx, larynx, trachea and oesophagus
  • anaphylaxis
  • foreign body
  • facial trauma
  • facial or respiratory burns
  • prior to extensive head and neck surgery
  • vocal cord paralysis
  • sleep apnoea
  • instable cervical spine
  • inflammation
  • tumor
  • congenital anomalies (structural or functional anomalies which occur in-utero)

NOTE: Tracheostomy is preferred as a prolonged airway maintenance and ventilation method. It is also used in cases of failed and/or repeated intubation, following intubation complications, and where there is need for deep secretion removal.

Tracheostomy Advantages

  • less restricting for the patient
  • enables swallowing
  • enables better communication
  • less sedation requirement
  • allows better mouth hygiene
  • helps avoid upper airway complications related to ETT use
  • easier secretion removal
  • reduces anatomical dead space (shorter, wider and less curved tube = better breathing = quicker weaning from ventilator use)

Tracheostomy Preparation & Surgical Procedure

  • explain tracheostomy procedure to the patient and accompanying relatives
  • gain operation consent
  • ensure availability of needed drugs (sedatives/analgesics/muscle relaxants), blood in reserve, suction equipment, cautery machine (helps in cutting and stopping bleeding immediately and effectively), and procedure trolley
  • help patient in supine position with blanket roll between shoulder blades to ensure neck is adequately exposed.
  1. an incision is made between the sternal notch and cricoid cartilage
  2. a midline vertical incision is made to divide strap muscles
  3. thyroid isthmus between ligatures is divided
  4. cricoid is elevated along with the cricoid hook
  5. an incision is made through the tracheal wall
  6. a tracheostomy tube is inserted while the endotracheal tube is withdrawn
  7. cuff is inflated
  8. keyhole dressing is applied
  9. tube is secured either with tape around the neck or with stay sutures
  10. tube is connected to the ventilator tubing
tracheostomy nursing care
Retrieved from https://www.surgeryencyclopedia.com/St-Wr/Tracheotomy.html on 1st November 2022

Percutaneous Dilational Tracheostomy

As seen above, a surgical tracheostomy requires a surgical dissection to be made down to the trachea, the creation of a window in the trachea with the insertion of a tracheostomy tube for ventilation…

Compared to surgical technique, the percutaneous dilational tracheostomy (PDT) uses a modified Seldinger technique where the trachea is accessed with a needle and then a guidewire is inserted. The tracheostomy tube is introduced over the guidewire after dilation.

Rashid & Islam, 2017

Thus, a percutaneous dilational tracheostomy avoids surgical incision, is less traumatic, and carries a lower bleeding risk.

  1. a large bore needle is inserted into the tracheal lumen between the 2nd and 3rd ring
  2. a flexible guidewire is then inserted
  3. serial dilations are made
  4. tube is inserted

NOTE: Ideally, a percutaneous dilational tracheostomy are done under ultrasound or bronchoscopy guidance. The procedure is contraindicated in patients with goitre, obesity, and acute upper airway obstruction.

Tracheostomy Complications

During placement of tracheostomy, arising complications may include:

  • haemorrhage (due to the area being very vascular)
  • pneumothorax (accidental pleura laceration)
  • oesophageal trauma
  • laryngeal nerve injury (may cause hoarseness, difficulty in swallowing or breathing, or loss of voice)
  • vagal nerve stimulation (may lead to bradycardia, hypotention, or cardiac arrest)
  • incorrect placement

Post-op complications following a tracheostomy may include:

  • haemorrhage
  • aspiration
  • wound infection
  • infection in the trachea
  • infection in the lungs
  • tube obstruction caused by blood or secretions
  • tube displacement
  • subcutaneous emphysema (usually this is solved without any interventions)

Late complications related to tracheostomy use may include:

  • tracheal stenosis (abnormal narrowing of the trachea which restricts the patient’s ability to breathe)
  • tracheo-oesophageal fistula (abnormal connection between the trachea and oesophagus which causes swallowed liquids or food to be aspirated into the lungs)
  • tracheoinnominate artery erosion by cuff or tip of tube (may require resuscitative and operative measures)
  • stoma does not close following removal of tube
  • overgranulation and scarring

Types of Tracheostomy Tubes

Retrieved from https://www.exportersindia.com/product-detail/white-fenestrated-tracheostomy-tube-6433292.htm (left) and https://www.magonlinelibrary.com/doi/abs/10.12968/bjon.2019.28.16.1060 (right) on 1st November 2022

Cuffed Tube with Disposable Inner Cannula – Used to obtain a closed circuit for ventilation.

  • Cuff should be inflated when using with ventilators
  • Cuff should be inflated just enough to allow minimal airleak
  • Cuff should be deflated if patient uses a speaking valve
  • Cuff pressure should be checked twice a day
  • Inner cannula is disposable
Retrieved from https://www.hopkinsmedicine.org/tracheostomy/about/types.html on 12th November 2022

Cuffed Tube with Reusable Inner Cannula – Used to obtain a closed circuit for ventilation.

  • Cuff should be inflated when using with ventilators
  • Cuff should be inflated just enough to allow minimal airleak
  • Cuff should be deflated if patient uses a speaking valve
  • Cuff pressure should be checked twice a day
  • Inner cannula is not disposable; you can reuse it after cleaning it thoroughly
Retrieved from https://www.hopkinsmedicine.org/tracheostomy/about/types.html on 12th November 2022

Cuffless Tube with Disposable Inner Cannula – Used for patients with tracheal problems and for patients who are ready for decannulation.

  • Save the decannulation plug if the patient is close to getting decannulated
  • Patient may be able to eat and may be able to talk without a speaking valve
  • Inner cannula is disposable
Retrieved from https://www.hopkinsmedicine.org/tracheostomy/about/types.html on 12th November 2022

Cuffed Tube with Reusable Inner Cannula – Used for patients with tracheal problems and for patients who are ready for decannulation.

  • Save the decannulation plug if the patient is close to getting decannulated
  • Patient may be able to eat and may be able to speak without a speaking valve
  • Inner cannula is not disposable; you can reuse it after cleaning it thoroughly
Retrieved from https://www.hopkinsmedicine.org/tracheostomy/about/types.html on 12th November 2022

Fenestrated Cuffed Tracheostomy Tube – Used for patients who are on the ventilator but are not able to tolerate a speaking valve to speak.

  • There is a high risk for granuloma formation at the site of the fenestration (hole)
  • There is a higher risk for aspirating secretions
  • It may be difficult to ventilate the patient adequately
Retrieved from https://www.hopkinsmedicine.org/tracheostomy/about/types.html on 12th November 2022

Fenestrated Cuffless Tracheostomy Tube – Used for patients who have difficulty using a speaking valve.

  • There is a high risk for granuloma formation at the site of the fenestration (hole)
Retrieved from https://www.hopkinsmedicine.org/tracheostomy/about/types.html on 12th November 2022

Metal Tracheostomy Tube – Not used as frequently anymore. Many of the patients who received a tracheostomy years ago still choose to continue using the metal tracheostomy tubes.

  • Patients cannot get a MRI
  • One needs to notify the security personnel at the airport prior to metal detection screening
Retrieved from https://www.hopkinsmedicine.org/tracheostomy/about/types.html on 12th November 2022

CUFFED VS NON-CUFFED VS FENESTRATED

tracheostomy nursing care
Retrieved from https://www.mountsinai.org/files/MSHealth/Assets/HS/Care/ENT/General/TracheostomyEducationPatientsCaregivers2019.pdf on 1st November 2022

SINGLE VS DOUBLE TUBE

Double lumen tubes contain an inner cannula which can be removed for cleaning.

tracheostomy nursing care
Retrieved from https://www.jcvaonline.com/article/S1053-0770(15)00077-4/fulltext on 2nd November 2022

TRACHEOSTOMY VS LARYNGECTOMY

tracheostomy nursing care
Retrieved from http://sinaiem.org/foam/dont-fear-the-tracheostomy/ on 2nd November 2022

SHILEY TUBE

Upper Airway Bypass Effects

In normal upper airway functions there is humidification, warming and filtration of inspired air, ability to taste, smell and swallow, speech production by the passing of exhaled air through the larynx, and involvement in the cough reflex.

When bypassing the upper airway, lack of humidification leads to impaired mucociliary function, thicker secretions which can easily cause tube obstruction, as well as atelectasis (partial or full lung collapse) and infection. Similarly, air below body temperature may cause bronchoconstriction, reduced air flow, decreased PO2 (partial pressure of oxygen) and decreased SaO2 (oxygen saturation of arterial blood).

Humidification

Requirements for optimal gas exchange, which are in normal circumstances achieved through the upper airway, include:

  • a temperature of 37 degrees celsius
  • 100% humidity
  • filtered air

Adequate humidification may reduce the need for suctioning, thus, in situations where the upper airway is bypassed by an ETT or tracheostomy, an external method providing warmth, humidity and filtration is needed.

Through an external humidification system, inspired gas is passed over heated water with a set temperature of about 60 degrees celsius. As the air passes along the tubing, it cools down to around 37 degrees celsius when reaching the patient.

Although this system provides a setting similar to what is required for optimal gas exchange, it poses a couple of problems: it requires equipment care, it restricts patient mobility, and it may also become an infection source for the patient.

The HME Filter – Heat Moisture Exchanger

HME filters a.k.a. heat moisture exchanger filters are devices used in patients who are mechanically ventilated to help prevent mucus plugging and endotracheal tube occlusion due to lack of humidification.

HMEs are made of hydrophylic material which retains heat and moisture in exhaled air, which are then recycled in subsequent inspirations, following filtration of inspired air.

HMEs improve patient mobility and lower risk of infection. However, they can still become easily blocked by secretions, and so, require frequent filter changes (usually changed within a couple of days based on manufacturer’s recommendations) or even cessation of use in case of profuse secretions.

tracheostomy nursing care
Retrieved from https://www.atosmedical.ca/support/heat-and-moisture-exchanger-hme/ on 2nd November 2022

Suctioning in Airway Management

Secretions are cleared by coughing under normal conditions. Cough involves pressure build-up in the lungs which depends on closure of the glottis. The use of a tube prevents the patient from increasing enough abdominal pressure to produce a cough that clears secretions in the airway. Additionally, the tube may also cause irritation which leads to increased sputum production.

Suctioning is a procedure that needs to be performed as often as required based on the patient’s individual needs, so as to clear secretions and maintain a patent tube.

  • suctioning should not be performed routinely but as needed
  • suctioning should be performed using a sterile technique
  • suctioning can be scary and unpleasant for the patient, thus, it needs to be performed with confidence and speed

Suctioning Indications

  • coughing
  • respiratory distress
  • increased peak airway pressure
  • decreased SaO2 (oxygen saturation of arterial blood) and PO2 (partial pressure of oxygen)
  • audible and/or visible secretions
  • suspected aspiration
  • signs of discomfort

Open Suctioning Procedure

  1. explain procedure to the patient
  2. provide the patient with hyperoxygenation at 100% oxygen
  3. whilst keeping the catheter in its wrapper, attach it to suction tubing and switch it on
  4. wear mask and sterile suction glove
  5. insert catheter up to 1cm more than the tube length
  6. apply suction on the way out; oropharyngeal cavity may also need suctioning
  7. hyperoxygenate again
  8. monitor patient

NOTES:

  • do not exceed 15 seconds in performing suctioning so as to prevent hypoxia
  • maintain aseptic technique whilst performing procedure
  • catheter width should not exceed half the tube’s diameter
  • catheters with multiple eyes produce less damage
  • negative pressure should not exceed 120mmHg
  • instillation of saline is not recommended any more, however, saline nebulisation may help in loosening secretions

Suctioning Complications

HYPOXAEMIA – arterial blood oxygen level lower than normal: happens due to the patient being disconnected from the oxygen source whilst suctioning is being performed; reduce risk by performing suctioning for not longer than 15 seconds and ideally using a closed suction system instead of the open suction one.

ATELECTASIS – complete or partial collapse of the entire lung or lobe of the lung: happens when excessive pressure is being used while suctioning; reduce risk by ensuring that pressure does not exceed 120mmHg.

BRONCHOSPASM – tightening of the muscles lining the bronchi a.k.a. airway tightening: happens due to catheter use stimulating the airway.

DYSRHYTHMIAS – abnormal or irregular heartbeat (especially bradycardia following suctioning): happens due to hypoxaemia and vagal stimulation.

HAEMODYNAMIC CHANGESincreased blood pressure and intracranial pressure; reduce risk by avoiding suctioning in patients with head injury.

TRACHEAL MUCOSA TRAUMA – reduce risk by avoiding deep suctioning, large catheters and excessive pressure.

INFECTIONreduce risk by using strict aseptic technique and using a closed suction system. NOTE: send specimens for C+S if infection is suspected.

Closed Tracheal Suctioning Procedure

Using a closed tracheal suctioning procedure allows suctioning of the airways without the need for disconnecting the patient from the ventilator. This is done by attaching the suction catheter in plastic sleeve directly to the ventilator tubing.

Advantages:

  • maintains oxygenation and PEEP (Positive End Expiratory Pressure) during suction
  • reduces the risk of complications related to hypoxaemia
  • provides HCPs with protection from secretions

Disadvantages:

  • possible auto-contamination (reduce risk by cleaning catheter after each use and change every 24 hours)
  • inadequate removal of secretions
  • extra weight on ventilator tubings may cause an unintentional extubation
  • expensive

Cuff Management

The use of a cuff provides a seal in mechanical ventilation of a patient. This seal provides protection from gross aspiration. However, it does not offer complete protection from aspiration, and it may also disguise aspiration signs. Additionally, cuff exerts pressure on the oesophagus, anchoring the larynx, thus reducing laryngeal elevation. Considering all the above…

The patient with an inflated cuff should be kept nil-by-mouth! Provide needed nutrition through a nasogastric tube, a nasojejunal tube, gastrostomy, or jejunostomy. Important: assist the patient as needed to maintain oral hygiene!

Cuff used should be a high volume low pressure cuff. Cuff pressure should be checked at the start of every shift, after turning the patient, after physiotherapy, after dressing change and if a leak can be heard. Pressure should be kept between 15-25mmHg.

A low cuff pressure causes a drop in tidal volume due to leak of exhaled air around the tube, as well as possible aspiration of gastric content.

A high cuff pressure may create a fistula between the trachea and the oesophagus a.k.a. tracheoesophageal fistula, especially if a stiff nasogastric tube is being used on the patient. It may also cause obstruction of capillary blood flow within the tracheal wall, leading to pressure sore necrosis and tracheal stenosis following formation and healing of scar tissue.

Tracheostomy Communication Through Speaking Valves

In normal circumstances, speech is created by the passing of exhaled air through the vocal cords. Since tracheostomy tubes are inserted below the vocal cords, sound cannot be formed. This may cause the patient to become anxious and feeling isolated.

The nurse should provide reassurance to the patient by explaining that loss of sound being experienced is only temporary, and voice returns once the tracheostomy tube is removed. The nurse should also encourage the patient to use different ways of communication whilst with a tracheostomy tube is inserted, such as using electronic devices, paper and pen, or speaking valves.

Speaking Valve Use

  1. When using a speaking valve, ensure that the patient has a good gag reflex and that he is using either a non-cuffed or a fenestrated tube; if patient is using a cuffed tube, ensure that the cuff is totally deflated before attempting use of speaking valve
  2. Upon inspiration, the valve opens, allowing air to be inhaled through the tracheostomy
  3. Upon exhalation, the valve closes; air passes around the tube and through the vocal cords, enabling exhalation from the upper airway and voice production

NOTE: DO NOT USE A SPEAKING VALVE if the patient has poor lung compliance, in the case of excessive secretions, and if laryngeal or pharyngeal problems are present.

tracheostomy nursing care
Retrieved from https://www.bsuh.nhs.uk/library/wp-content/uploads/sites/8/2021/08/Tracheostomy-tubes-and-safety-1.0.pdf on 4th November 2022

Tracheostomy Nursing Care – Wound Care & Tape Changes

The surgical wound needs to be kept clean and dry at all times. The wound dressing used needs to be changed daily or whenever it becomes soiled. The aseptic non-touch technique should be used whilst cleaning the wound with saline, including careful cleaning of the area underneath the flange. Note that between the patient’s neck and tape there needs to be a space for one to two fingers.

prepared equipment for an arising emergency

  • 1 spare tube in the same size as the one being used
  • 1 spare tube in a smaller size than the one being used
  • suction and suction catheters
  • oxygen
  • tracheostomy mask
  • securing tape
  • tracheal dilators
  • scissors
  • suture cutter
  • lubricating gel
  • syringe (to inflate cuff)
  • drugs and equipment for resuscitation
  • sterile keyhole dressing
  • non-sterile gloves

Tracheostomy Tube Change

A single lumen tracheostomy tube should be changed every 7-10 days so as to prevent obstruction. Other indications for a tracheostomy tube change include:

  • cuff failure
  • blockage within the tube
  • displacement of the tube
  • needing to change to a larger or smaller tube

Tracheostomy Weaning and Decannulation

A tracheostomy is no longer needed if:

  • the reason for a tracheostomy has been resolved
  • the patient is alert, stable, and self ventilating on air
  • the patient has no significant signs of airway obstruction
  • the patient is able to swallow and cough up secretions
  • the patient is able to maintain good oxygen saturation

In case of the above:

  1. cuff is deflated
  2. tube is occluded for 24 hours
  3. if no respiratory distress is experienced by the patient, tube is removed
  4. the stoma is covered with a small occlusive dressing

Important Tracheostomy Nursing Care Observations

  • monitor patient for bleeding or oozing
  • monitor patient for signs of infection and/or inflammation
  • monitor patient for evidence of tissue damage
  • monitor cuff pressure and ensure it is kept within normal limits
  • monitor amount, colour and consistency of secretions

Reference

Johns Hopkins Medicine (n/d). Tracheostomy Service. Retrieved from https://www.hopkinsmedicine.org/tracheostomy/about/types.html on 12th November 2022

Rashid, A. O., & Islam, S. (2017). Percutaneous tracheostomy: a comprehensive review. Journal of thoracic disease, 9(Suppl 10), S1128โ€“S1138. https://doi.org/10.21037/jtd.2017.09.33


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WASP International Scientific Paper Writing Course

WASP International Scientific Paper Writing Course is an intensive three-day event with formal lectures & interactive sessions delivered by highly experienced researchers and journal editors. All aspects of paper writing are covered, from proposals, to presenting to dealing with journal editors. Statistical analysis is demonstrated within Excelยฎ and includes hands on sessions on attendeesโ€™ own laptops. Excel modules used for analysis are given to attendees along with soft copies of the presentations.

Research and Publication are Career Critical! WASP International Maximises YOUR Chances of Getting Published!

Since 2010, over 20 WASP Courses have already been held, specifically in Malta, London, Bahrain and online. WASP International Scientific Paper Writing Course is suitable for all individuals in the sciences who wish to enhance their paper writing skills by acquiring sound competences in academic writing. WASP International is not only intended for the medical profession: engineers, architects, pharmacists, nurses etc. have all joined, enjoyed and benefited from WASP.

WASP International covers all aspects of paper writing:

  • literature review
  • proposal
  • grant
  • ethics
  • data protection
  • data collection
  • analysis
  • writing
  • abstracts/posters/presentations
  • paper formatting
  • referencing software
  • submission
  • peer review
  • dissertation
  • facilitated statistics using Excelโ„ข

At the end of the WASP event, attendees are also presented with a certificate of attendance attesting to the 18 CME points that are allotted to this event via the Medical Association of Malta (MAM).

More details about the WASP Faculty can be found here.

We practice what we preach in WASP โ€“ all of the talks (as well as related topics) have been published in the peer-reviewed journal (impact factor 2.2) Early Human Development in a series of medical education sections in consecutive issues of the journal. See PubMed link.

Prof. Victor Grech, creator and director of WASP.

WASP has now been endorsed by the Royal College of Paediatrics and Child Health for the equivalent of 18 category 1 (external) CPD credits. In addition, the course is also endorsed by the following international and local bodies:

Now is your chance to learn scientific paper writing the proper way. An early bird registration and discount are currently available. You may register at http://www.ithams.com/wasp/ (there is an early bird registration and discount…make sure you don’t miss out!!)


Are you organising events or have products or information that can enhance the knowledge of local and international student nurses on their way to registration? I’d love to hear from you! Contact me here

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Oropharyngeal Nasopharyngeal and Endotracheal Tubes

Airway management in the critical care setting depends on 4 steps which, when followed adequately, ensure patient’s safety:

  1. timely clinical identification of airway compromise in patient
  2. use of the most appropriate airway maneuver for the patient
  3. appropriately choosing and introducing airway adjuncts
  4. becoming aware if and when the need for ventilation arises, and delivering it effectively

Oropharyngeal and Nasopharyngeal airways are tubes made of plastic or rubber used to help maintain airway patency by keeping the tongue out of the way from obstructing the upper airway. Whilst in use, patient breathing should be assessed and confirmed so that proper positioning is ensured.

endotracheal tubes
Retrieved from https://twitter.com/myway_rt/status/1472980655696973825?lang=ar-x-fm on 28th October 2022

Complications

  • gagging
  • vomiting (may lead to aspiration)
  • bleeding following trauma to the oral or nasal cavity
  • airway obstruction caused by the oropharyngeal airway pushing the tongue to the back
  • laryngospasm – vocal chord spasm which causes temporary difficulties with breathing and speaking

NOTE: The oropharyngeal airway should only be used in unconscious patients with an absent gag reflex.

NOTE: Do not use the nasopharyngeal airway on patients with a fractured skull base.

Oropharyngeal & Nasopharyngeal Airway Insertion

Oral & Nasal Endotracheal Tubes

Oral endotracheal tubes are commonly used in emergency situations. Whilst oral ETTs can be inserted easily, they also facilitate insertion of a larger tube that facilitates breathing and secretion suctioning.

Nasal endotracheal tubes provide less discomfort to the patient since they enable swallowing and oral hygiene, as well as facilitate communication. They can be easily secured and stabilised, minimising the risk of unintentional extubation. Additionally, a nasal ETT is preferred for paediatric use, post-extensive dental or neck surgery, and for patients with a fractured jaw.

Endotracheal tubes are available in many sizes. At the distal end of an endotracheal tube is a cuff which can be inflated by an external pilot balloon using between 15 to 25ml of water. This helps the ETT to stay in place, helps keep ventilated air in the ETT without escaping back up, and may also help prevent aspiration (although micro-aspiration can still pass through). At the proximal end a 15mm adaptor can be attached. This adaptor enables the ETT to be connected to ventilator tubings or to manual resuscitation bags.

NOTE: in paediatrics, the ETT used is usually without a cuff, which means it can be easily coughed out.

Intubation Equipment

  • ETTs (different sizes)
  • Stylet and Boogie (used in difficult intubations)
  • Checked Suction
  • Suction Catheters
  • Manual Resuscitation Bag (connected to oxygen)
  • Ventilation Masks
  • Laryngoscope Handle + Blades (pre-checked)
  • IV Access
  • Haemodynamic and Respiratory Monitoring Equipment

Use of McCoy Laryngoscope & bougie

The McCoy laryngoscope’s blade has an adjustable hinged tip for improved visualisation of the vocal cords during difficult intubations.

Intubation Drugs

  • analgesics
  • sedatives (short-acting) eg. Etomidate or Propofol
  • muscle relaxants (short-acting) eg. Suxamethonium (Scoline) or Atracurium (Tracrium)
  • resuscitation drugs eg. adrenaline or atropine

NOTE: when ventilating a patient, it is very important to administer sedation first. When sedation effects kick in, a muscle relaxant can then be administered. Baseline parameters are then taken and patient is continuously monitored.

Intubation Procedure

  1. prepare equipment and ensure that all is checked and in working order
  2. position patient in a way which ensures airway patency
  3. suction the patient’s oral cavity and the pharynx
  4. provide patient with 100% oxygen through manual ventilation for a few minutes
  5. attempt intubation – limit attempt/s to 30 seconds
  6. use the BURP technique to increase visibility (apply pressure on thyroid cartilage whilst moving backward, upward, and rightward)
  7. insert tube and inflate cuff
  8. ensure correct tube positioning through auscultation of bilateral breath sounds, visible chest rise, x-ray imaging, and ETCO2 monitor
  9. document size and depth of ETT used

ATTENTION: if the ETT is misplaced into the stomach and not in the trachea, upon ventilating with 100% oxygen, the stomach would inflate instead of the lungs – chest.

Intubation Complications

  • vomiting and aspiration
  • laryngospasm
  • trauma to the mouth, nose, pharynx, trachea and/or oesophagus
  • gastric intubation
  • right main bronchus intubation
  • hypoxaemia and/or hypercapnia leading to hyper/hypotension and tachy/bradycardia
endotracheal tubes
Right Bronchus Intubation – Retrieved from http://learningradiology.com/archives04/COW%20129-Atelectasis-ETT/atelectasiscorrect.htm on 28th October 2022

Prolonged Intubation Complications

  • patient discomfort
  • communication difficulty
  • patient anxiety
  • hypersalivation
  • tube displacement
  • tube obstruction
  • aspiration
  • nasal injury
  • mucosal lesions
  • cricoid abscess – causes airway compromise reversible with treatment
  • sinusitis – causes nasal discharge and undetermined fever
  • laryngeal stenosis – scarring within the larynx at or above the vocal cords which limits the larynx from opening as it normally does
  • tracheal stenosis – unusual narrowing of the trachea which restricts normal breathing
  • tracheo-oesophageal fistula – unusual connection between the trachea and oesophagus which causes swallowed liquids and foods to be aspirated into the lungs

NOTE: An ETT should not be used for more than 12 days. If further ventilation is required, a tracheostomy should be considered instead.


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