Patient Hospital Admission

Patient hospital admission refers to the admission and acceptance of a patient into a health facility with the aim of staying under observation, undergoing necessary diagnostic investigations, and receiving required medical or surgical treatment. Patient hospital admission can be either elective – where a procedure is planned beforehand, or an emergency.

Elective Admission

In an elective patient hospital admission, a healthcare professional agrees with the patient on a convenient date for admission. This enables the patient to prepare in advance for the procedure.

Emergency Admission

In an emergency patient hospital admission, the patient is usually brought in by relatives or friends in a critical condition. In such an admission, the patient is usually transported by a wheelchair or a stretcher to an adequate ward for immediate evaluation and treatment.

Elective Patient Hospital Admission Procedure

  1. Welcome the patient and any accompanying relatives to the ward and introduce yourself and any other present HCPs
  2. Gather all required documents such as admission papers and other important information or documentation from the accompanying nurse
  3. Confirm patient identity through given details
  4. Ensure that the patient and accompanying relatives feel welcomed and comfortable
  5. Gather any additional required information by the patient and/or the accompanying relatives
  6. Provide a hospital bed located at an ideal room for the patient in question, based on the patient’s health requirements and condition
  7. Provide assistance to the patient to change into pyjamas or hospital gown and ensure identification bracelet and any other required tags eg. allergy bracelet is provided
  8. Take baseline vital signs and document
  9. Collect any required specimens if needed
  10. Administer any urgent medications
  11. Ensure patient valuables are taken care of
  12. Ensure informed consent is obtained, signed by the patient
  13. Inform relatives about visiting hours and about anything that they may need to bring in for the patient on their next visit
  14. Following relatives’ departure from the ward, orient patient to the ward and to the surrounding environment
  15. Provide nursing care based on The Nursing Process
  16. Input the patient’s particulars in the admission and discharge book
  17. Document admission into the patient’s nursing documentation sheet
  18. Input ward state (bed availabilities), risk of pressure injuries and any required equipment based on the patient’s admission condition into the online system

Emergency Patient Hospital Admission Procedure

  1. Perform hand hygiene
  2. Gather emergency equipment– vital signs apparatus, resuscitation trolley, oxygen, venepuncture equipment, suction apparatus, and an adequate bed in a suitable location based on the patient’s condition
  3. Welcome the patient and accompanying relatives to the ward and introduce yourself and any other present HCPs
  4. Gather all required documents such as admission papers and other important information or documentation from the accompanying nurse
  5. Confirm patient identity through given details
  6. Assess patient’s overall condition efficiently
  7. Receive patient into a previously prepared bed, keeping the patient’s current condition in mind
  8. Provide assistance to the patient to change into pyjamas or hospital gown and ensure identification bracelet and any other required tags eg. allergy bracelet is provided
  9. Take baseline vital signs and observe further the patient’s overall appearance and reaction, level of consciousness, skin integrity, pain, breathing pattern, and any other complaints, and document
  10. Collect relevant history from the patient or accompanying relatives
  11. Ensure informed consent is obtained, signed by the patient (include detailed information about required emergency procedures is given to ensure informed consent)
  12. Ensure patient valuables are taken care of
  13. Inform relatives about visiting hours and about anything that they may need to bring in for the patient on their next visit
  14. Following relatives’ departure from the ward, orient patient to the ward and to the surrounding environment
  15. Collect any required specimens if needed
  16. Administer prescribed medications
  17. Input ward state (bed availabilities), risk of pressure injuries and any required equipment based on the patient’s admission condition into the online system
  18. Document admission into the patient’s nursing documentation sheet

The Nurse’s Role in the Admission Process

  • Ensure the patient’s physical and emotional needs are met
  • Ensure the patient is assigned to a bed adequate to his/her personal needs and condition
  • Ensure that the patient’s admission report is completed
  • Ensure the patient is assessed using The Nursing Process
  • Provide a holistic approach to patient care based on the Activities of Daily Living guide whilst considering the patient’s psychological, social, spiritual, and cultural needs
  • Ensure the patient’s comfort and aim to reduce anxiety in both the patient and accompanying relatives
Patient Hospital Admission
Retrieved from https://nurseslabs.com/nursing-diagnosis/ on 7th November 2021
Retrieved from https://nurseslabs.com/nursing-diagnosis/ on 7th November 2021

Transferring the Patient

During a hospital stay, the patient may require transferring from one ward to another within the same healthcare facility.

Transfer in

In a Transfer-In, a patient is moved from one unit to another, eg. from a medical to a surgical ward.

When a patient is being transferred in:

  1. ensure a suitable bed is available to receive the patient
  2. ensure all necessary equipment depending on the patient’s condition is readily available
  3. ensure the patient, accompanying nurse, and any accompanying relatives are received warmly
  4. ensure correct handover, transfer of notes, and any patient personal belongings are received from the accompanying nurse
  5. confirm patient identity with accompanying nurse
  6. clarify any queries pertaining to the patient’s condition
  7. introduce yourself and other present HCPs to the patient and accompanying relatives
  8. assess patient’s overall condition efficiently
  9. ensure the patient is assessed using The Nursing Process
  10. orient patient and relatives to the ward and to the surrounding environment
  11. input ward state (bed availabilities), risk of pressure injuries and any required equipment based on the patient’s admission condition into the online system, including time of admission
  12. document transfer into the patient’s nursing documentation sheet

Transfer Out

In a Transfer-Out, the patient can be transferred from one ward to another, or from one facility to another.

When transferring a patient out:

  1. confirm transfer with receiving unit
  2. assess the patient’s condition
  3. arrange for a nurse to accompany the patient
  4. plan for an appropriate transferring vehicle if required
  5. collect all patient data
  6. reduce the patient’s and accompanying relatives’ anxiety by explaining reason for transfer
  7. obtain informed written consent for transfer
  8. assist in the packing of the patient’s personal belongings
  9. ensure patient’s medication, diagnostic results, and transfer notes, are all compiled as required
  10. assist patient in dressing up adequately for the transfer
  11. assist patient into a wheelchair or stretcher, and into an ambulance, if required
  12. ensure patient’s notes and belongings are handed over to the accompanying nurse
  13. input ward state (bed availabilities), risk of pressure injuries and any required equipment based on the patient’s admission condition into the online system, including time of transfer
  14. document transfer into the patient’s nursing documentation sheet

Discharging the Patient from the Hospital

Discharge planning should start shortly after the patient is admitted, and is usually done at the discretion of the medical team, based on the patient’s overall health condition, or if the patient requests to be discharged. The patient and his/her relatives should always be informed about intended discharge plans.


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Haemostasis ~ The Blood Clotting Process

Haemostasis

Haemostasis is the process by which blood loss is prevented. This happens through three basic mechanisms:

  1. Vascular Spasm – blood vessel damage stimulates pain receptors to cause immediate smooth muscle contraction within its wall; this reduces blood loss rate for up to 30 minutes, during which other haemostatic mechanisms are triggered.
  2. Platelet Plug Formation – platelets which come into contact with damaged blood vessel parts begin to enlarge, become irregular, sticky, and start adhering to collagen fibres; ADP (adenosine diphosphate) and enzyme synthesis triggers the formation of other substances, activating more platelets to adhere to the original platelets, forming a platelet plug, which is then reinforced by fibrin threads.
  3. Blood Coagulation a.k.a. Blood Clotting -whilst blood within the vessels maintains its liquid state, blood outside the vessels thickens and forms a gel (serum) which separates from the liquid. Blood serum is blood plasma without its clotting proteins, whilst the gel is the clot, which contains insoluble fibres that trap the cellular components of the blood.
Retrieved from https://quizlet.com/185065266/hemostasis-vs-anticoagulation-and-thrombolysis-flash-cards/ on 22nd May 2022

Blood Coagulation

Blood coagulation is the process of clot formation – a process which involves various chemicals referred to as coagulation factors.

haemostasis coagulation factors
Retrieved from https://www.vetfolio.com/learn/article/hemostasis on 22nd May 2022

There are 3 basic stages for coagulation…

Stage 1: Formation of Prothrombin Activator

Stage 1 involves the formation of prothrombin activator, initiated by the extrinsic and intrinsic pathway of blood clotting.

Stage 2: Conversion of Prothrombin into Thrombin

Following the formation of prothrombin activator, it binds to Ca2+ ions (Calcium Ions), causing the conversion of prothrombin into thrombin.

Stage 3: Conversion of Fibrinogen into Fibrin

Thrombin and Ca2+ ions trigger the conversion of Fibrinogen (soluble) to Fibrin (insoluble).

Thrombin activates Factor XIII (Antihemophilic Factor) which strengthens and stabilises the fibrin clot.

Through a positive feedback effect, Thrombin accelerates the formation of prothrombin activator through Factor V (Proaccelerin), which further accelerates the production of more Thrombin.

The formed clot plugs the ruptured area of the blood vessel, preventing haemorrhage. This is followed by permanent repair of the blood vessel.

Additional Factors related to Haemostasis

Vitamin K

Efficient clotting requires Calcium as well as Vitamin K, which is required for prothrombin formation and other coagulation factors by the liver. Vitamin K is formed by the human intestinal bacteria, and can also be found in foods such as spinach, cabbage, cauliflower, and liver.

Thrombosis

Thrombosis is the formation of a clot (thrombus) within an intact blood vessel. Thrombosis is caused within blood vessels containing sluggish blood flow, and when platelets stick to fatty deposits on the blood vessels’ inner surface. A thrombus can either dissolve or else grow and eventually block the blood vessel.

Embolism

Embolism happens when a part of the thrombus breaks off from its original site forming an embolus, moves along the blood stream until it reaches a small blood vessel and blocks it.


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Blood Disorders

Blood disorders have an impact on the main components of the bloodred blood cells, which carry oxygen throughout the body; white blood cells, which fight infection; and platelets, which help through their blood clotting mechanism. Some blood disorders are caused by genes. However, blood disorders can also result from other diseases, medications, or lack of nutritional intake.

Diagnostic Tests for Blood Disorders

  • CBC (Complete Blood Count) – haemoglobin, haematocrit, reticulocyte count, red blood cell indices, MCV (mean corpuscular volume i.e. RBC size), and RDW (RBC distribution width)
  • Blood Chemistry Tests – Electrolytes, Fats, Proteins, and Glucose
  • Blood Enzyme Tests – Myoglobin, Troponin, and Creatine-Kinase
  • Blood Clotting Tests – PT (Prothrombin Time), aPTT (activated partial thromboplastin time), TT (Thrombin Time)
  • Serum Vitamin B12 and folate levels, haptoglobin, erythropoietin levels
  • Bone Marrow aspiration
Retrieved from https://www.rch.org.au/clinicalguide/guideline_index/Anaemia/ on 19th May 2022

Anaemia

Anaemia is a blood disorder in which there is a deficiency in erythrocytes or haemoglobin, leading to tissue oxygen deprivation.

Causes

  • bleeding (eg. menstruation, childbirth, NSAIDs overuse [may cause ulcers and gastritis], GI conditions [ulcers, haemorrhoids, gastritis and cancer]
  • decreased or abnormal RBC production (eg. sickle-cell anaemia, iron-deficiency anaemia, vitamin deficiency, problems related to the bone marrow and/or stem cells)
  • premature RBC destruction (RBCs inability to withstand circulation stress, leading to premature rupture, causing haemolytic anaemia)

Possible complications

  • Confusion
  • Parathesias (a burning or prickling sensation usually felt in the hands, arms, legs, or feet, but can also extend to other body parts)
  • Congestive Heart Failure
  • Death

1. Iron-Deficiency Anaemia

Iron-Deficiency Anaemia is a type of anaemia in which there is lack of iron in the body. Iron is required for the production of haemoglobin for red blood cells to carry oxygen throughout the body.

2. Pernicious Anaemia

Pernicious Anaemia is a type of anaemia in which the intrinsic factor is missing. This results in lack of Vitamin B12 absorption. While Pernicious Anaemia is very common in older individuals and individuals who have had a gastric resection, it may also result from malnutrition in which B12 intake is low, such as in vegetarian diets or lack of dairy products intake.

3. Aplastic Anaemia

Aplastic Anaemia is caused by a deficiency of all blood cell types due to bone marrow development failure. Aplastic Anaemia is considered to be a rare disease.

4. Thalassemia

The term ‘Thalassemia’ refers to a group of hereditary disorders in which there is defective haemoglobin-chain synthesis. In Thalassemia there is an abnormal decrease in RBCs’ haemoglobin (hypochromia), small RBCs (microcytosis), blood element destruction (haemolysis) and anaemia.

Anaemia Clinical Manifestations

Retrieved from https://medlineplus.gov/genetics/condition/iron-refractory-iron-deficiency-anemia/ on 19th May 2022
Retrieved from https://www.kindpng.com/imgv/hiRwoTJ_symptoms-of-anaemia-symptoms-of-anemia-hd-png/ on 19th May 2022

Anaemia Nursing Care

Assessment

  • What type of anaemia is involved?
  • What symptoms is it exhibiting, and to what extent?
  • How are these symptoms leaving an impact on the patient’s daily life?
  • What medication has the patient been on – past and present? Was the patient on medications which may have caused a reduction in bone marrow activity, caused haemolysis, or affected folate metabolism?

Diagnosis

  • Fatigue (due to haemoglobin decrease i.e. reduced oxygen saturation)
  • Malnutrition (lack of required nutrition and nutrient intake)
  • Decreased Tissue Perfusion (due to reduced blood volume – hematocrit)
  • Poor Medication Compliance

Implementation

  1. ensure adequate rest to reduce fatigue along with periods of feasible activities to promote physical activity, whilst also assessing for other conditions such as pain, depression, and insomnia, which may further exacerbate fatigue
  2. encourage and/or ensure adequate nutritional intake through a healthy diet comprising of adequate iron, vitamin B12, folic acid, and protein intake (if required supplements may be recommended), whilst avoiding alcohol
  3. ensure adequate tissue perfusion through blood transfusions, IV fluids, and if required supplemental oxygen (monitor vital signs and SPO2)
  4. educate about the importance of medication compliance and management of side effects
  5. promote complication avoidance by assessing for heart failure, assessing the patient neurologically, evaluating the patient’s gait and balance, and complaints of parathesias

Evaluation

  1. assess for signs and symptoms of heart failure
  2. measure and document the patient’s weight on a daily basis
  3. intake and output charting
  4. assess for possible need of diuretics in the case of fluid retention

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Blood Groups and Blood Transfusions

Blood Groups

Erythrocytes contain antigens called agglutinogens or isoantigens which are genetically determined. At least, 300 blood group systems may be detected on red blood cells’ surface. However, the focus is on 2 major classifications of blood groups, namely the ABO Blood Grouping System and the Rhesus System.

ABO Blood Grouping System

  • there are 2 types of agglutinogens: Agglutinogen A and Agglutinogen B
  • individuals with red blood cells containing Agglutinogen A have a Blood Type A
  • individuals with red blood cells containing Agglutinogen B have a Blood Type B
  • individuals with red blood cells containing both Agglutinogen A and B have Blood Type AB
  • individuals with red blood cells containing NO Agglutinogen A and NO Agglutinogen B have Blood Type O

The BLOOD PLASMA contains antibodies called agglutinins or isoantibodies.

  • Agglutinin A attacks Agglutinogen A
  • Agglutinin B attacks Agglutinogen B
Retrieved from https://cbm.msoe.edu/crest/ePosters/a16gtaBloodType.html on 14th May 2022

Rhesus (Rh) System

  • the Rh system is based on the presence (or lack of) of agglutinogens which can be found on the surfaces of erythrocytes
  • individuals with red blood cells containing Rh agglutinogens are said to be Rh+
  • individuals with red blood cells containing NO Rh agglutinogens are said to be Rh-
Retrieved from https://www.scienceabc.com/humans/is-it-important-to-compare-blood-groups-with-your-partner.html on 14th May 2022

Blood Transfusions

Blood transfusions are commonly indicated for circulatory shock, anaemia (lack of healthy red blood cells leading to inadequate oxygen distribution to the body’s tissues), haemophilia (bleeding disorder, usually inherited, with an improper blood clotting mechanism), and haemolytic disease of the newborn (a disease in which there is fast destruction of red blood cells).

Incompatible blood transfusions may cause very bad consequences such as kidney damage, brain damage, and even death.

Further Information…

Red Cell Concentrates โ€“ indicated for anaemia and acute blood loss: help increase oxygen carrying capacity through raising haemoglobin concentration in the patient. Can be stored in a temperature of 4 +/-2ยฐC for 42 days (or for 28 days if irradiated). If unused or left for more than 30 minutes in the transport box, Red Cell Concentrates should be returned to the Blood Bank to minimise the risk of bacterial growth.

CMV (CytoMegaloVirus) Negative Blood: indicated for intrauterine transfusions, neonate transfusion (28 days post EDD) and pregnant women transfusion.

Irradiated Blood: indicated for intrauterine transfusion, BM/ stem cell transplantation, Hodgkinโ€™s disease, etc.

For more details on the administration of blood and blood components click here.


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Blood Components and Functions

The internal environment of the human organism is made up of blood within the blood vessels, interstitial fluid surrounding the body cells, and lymph inside the lymph vessels.

The blood is able to pick up:

  • nutrients (from the digestive tract)
  • oxygen (from the lungs)
  • hormones (from the endocrine glands)
  • enzymes (from multiple body sites)

The blood can also act as a transportation means for disease-causing organisms. For this reason, the lymphatic system helps in picking up wastes from the interstitial fluid, cleansing them of bacteria, and returning them bacteria-free into the blood.

Physical Characteristics of the Blood

blood components
Retrieved from https://quizlet.com/96941163/56-what-is-the-normal-ph-of-blood-181b-physical-characteristics-of-blood-flash-cards/ on 12th May 2022

Blood Functions

1. Transportation

Blood helps in the transportation of:

  • Oxygen (from the lungs to the body’s cells)
  • Carbon Dioxide (from the cells to the lungs)
  • Nutrients (from the digestive organs to the cells)
  • Waste Products (from the cells to the kidneys, lungs, and sweat glands)
  • Hormones (from the endocrine glands to the cells)
  • Enzymes (to various cells)

2. Regulation

Blood helps in the regulation of:

  • pH (through buffers)
  • Body Temperature (through heat-absorbing and coolant properties of its water content)
  • Water within the Cells (mainly through dissolved sodium ions)

3. Protection

Blood helps in protecting the body against:

  • Blood Loss (through the blood clotting mechanism)
  • Toxins and Foreign Microbes (through special combat-unit cells such as white blood cells)

Blood Composition

blood components
Retrieved from https://classnotes123.com/composition-of-blood-class-10/ on 12th May 2022

Blood is made up of 2 portions:

1. Formed Elements

  • make up 45% of the total blood volume
  • include Red Blood Cells, White Blood Cells (Granular – neutrophils, eosinophils & basinophils; and Agranular – lymphocytes & monocytes), and Platelets.

2. Plasma

  • makes up 55% of the total blood volume
  • water (91.5% of total plasma)
  • proteins (7% of total plasma)
  • other solutes (1.5% of total plasma)
blood components
Retrieved from https://twitter.com/drkeithsiau/status/1435631529372393476 on 12th May 2022

Haematopoiesis – Blood Cell Formation

Haematopoiesis a.k.a. blood cell formation takes place within the Red Bone Marrow (myeloid tissue in the humerus, femur, sternum, ribs, vertebrae & pelvis) and Lymphoid Tissue (in the spleen, tonsils & lymph nodes).

  • Red Blood Cells, Leucocytes & Platelets are produced within the Bone Marrow.
  • Agranular Leucocytes (lymphocytes & monocytes) are produced by the Bone Marrow and the Lymphoid Tissue.
blood components
Retrieved from https://www.pngkit.com/view/u2w7u2u2t4e6o0w7_hematopoiesis-is-the-formation-of-blood-cellular-components/ on 12th May 2022
blood components
Retrieved from https://www.researchgate.net/publication/324848224_An_In_Vitro_Model_of_Hematotoxicity_Differentiation_of_Bone_Marrow-Derived_StemProgenitor_Cells_into_Hematopoietic_Lineages_and_Evaluation_of_Lineage-Specific_Hematotoxicity/figures?lo=1 on 12th May 2022

Red Blood Cells a.k.a. Erythrocytes

  • do not contain a nucleus
  • cannot reproduce
  • cannot carry on extensive metabolic activities
  • plasma membrane is selectively permeable
  • plasma membrane encloses cytoplasm and haemoglobin
  • have a biconcave shape which promotes increased surface area for diffusion purposes
  • contain a lot of haemoglobin molecules which increase their capacity for oxygen transportation
  • allow transportation of a small amount of carbon dioxide along with haemoglobin

Normal Haemoglobin Values

Infants14-20gm/dl
Adult Females12-15gm/dl
Adult Males14-16.5gm/dl

Erythropoiesis – Erythrocyte Production

  • erythropoiesis and erythrocyte destruction usually proceed at the same pace
  • if the balance between erythropoiesis and erythrocyte destruction is disrupted, a homeostatic mechanism is initiated to promote erythrocyte production
  • in oxygen deficiency, particular kidney cells release the enzyme Renal Erythropoietic Factor which converts plasma protein into the hormone erythropoietin, which, when reaching the red bone marrow, stimulates haemocytoblasts to develop into red cells

NOTE: Blast is a short name for an immature WBC, such as a lymphoblast or myeloblast. In normal circumstances, less than 5% of the cells in healthy bone marrow at any one time are blasts. Within the bone marrow, normal blasts develop into mature, functioning blood cells and are then released into the bloodstream.

Retrieved from https://labpedia.net/erythropoiesis-rbc-maturation-rbc-counting-procedure/ on 12th May 2022

Haemoglobin in Erythrocytes

  • erythrocyte life span is around 120 days long
  • the plasma membrane of depleted cells are removed from the circulation by macrophages in the spleen, liver, and bone marrow
  • haemoglobin is broken down into Haemosiderin (iron-containing pigment which is stored or used in the bone marrow for the production of new haemoglobin for new RBCs), Bilirubin (pigment secreted by the liver into bile) and Globin (protein metabolised in the liver).
haemoglobin
Retrieved from https://www.vedantu.com/question-answer/the-protein-part-of-haemoglobin-is-a-globin-b-class-10-biology-cbse-5f7da8c25c3c1346af535ef9 on 12th May 2022

White Blood Cells a.k.a. Leucocytes

  • there is a much lesser amount of WBCs than RBCs in the human body: 700 RBCs per 1 WBC
  • leucocytes contain nuclei
  • leucocytes do NOT contain haemoglobin
  • leucocytes have surface proteins called Human Leucocyte Associated Antigens (HLA) which are unique to each and every person

There are 2 types of WBCs:

GRANULAR LEUCOCYTES:

  • NEUTROPHILS (POLYMORPHS) – make up the biggest amount of total leucocytes; involved in phagocytosis of bacterial pathogens and the release of antimicrobial chemicals
  • EOSINOPHILS – involved in phagocytosis of antigen-antibody complexes, allergens and inflammatory chemicals, and the release of enzymes which help weaken or destroy parasites
  • BASOPHILS – involved in the secretion of histamine which promotes blood flow to a particular tissue, and the secretion of heparin which promotes mobility of other WBCs by clotting prevention
  • develop from red bone marrow
  • have granules in the cytoplasm
  • have a lobed nuclei

AGRANULAR LEUCOCYTES:

  • MONOCYTES – turn into macrophages; phagocytise pathogens, dead neutrophils, and dead cells debris; and present antigens that activate other cells within the immune system
  • LYMPHOCYTES – assist with immune memory, secrete antibodies, present antigens for the activation of other cells within the immune system, and help in destroying cancer cells, virus-infected cells, and foreign cells
  • develop from lymphoid and myeloid tissue
  • do not have granules in the cytoplasm
Retrieved from https://www.pinterest.com/pin/452752568781425426/ on 13th May 2022

Differential Blood Count

Type of White Blood CellNormal Differential CountHigh WBC Count Implication
Neutrophils60% – 70%damage caused by invading bacteria
Eosinophils2% – 4%allergic reaction
Basophils0.5% – 1%allergic reaction
Lymphocytes20% – 25%antigen-antibody reaction
Monocytes3% – 8%chronic infection

Life Span of Leucocytes

  • leucocytes can live from just a few days to a few months, depending on what type of leucocytes they are
  • during infection, white blood cells become very active, usually living for only a few hours

Platelets

  • platelets contain no nucleus
  • platelets have a life span of between 5 to 9 days
  • platelets help prevent fluid loss through a chain of reaction leading in blood clotting
  • stem cell development from haemocytoblast to platelets takes place in the red bone marrow
Stem cell developmental pathway. Retrieved from https://slideplayer.com/slide/12774626/ on 14th May 2022

Plasma

Plasma is made up of:

  • WATER – 90% of total amount of water in plasma is derived from the GI tract; 10% is derived from cellular respiration; water absorbs heat and acts as a solvent and suspending medium for the blood’s solid components
  • SOLUTES – makes up 8.5% of the total plasma volume
  • PROTEINS – ALBUMINS (55% of plasma proteins) are produced by the liver; provide viscosity in the blood which helps maintain blood pressure; exert osmotic pressure to help in maintaining water balance between the blood and the tissues; help regulate blood volume; GLOBULINS (38% of plasma proteins) a.k.a. antibodies; FIBRINOGEN (7% of plasma proteins) is produced by the liver; it helps in the blood clotting process
blood plasma components
Retrieved from https://www.austincc.edu/apreview/PhysText/Blood.htm on 14th May 2022

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Thyroid Disease & Patient Education Based on NICE Guidelines

The phrase thyroid disease refers to medical conditions which affect the way the thyroid gland works. The thyroid gland typically produces an amount of hormones which help the body to function well. Too much thyroid hormone production is referred to as hyperthyroidism, whilst too little thyroid hormone production is referred to as hypothyroidism.

Retrieved from https://www.easyyogasan.com/thyroid-test-t3-t4-tsh-normal-range/ on 10th May 2022

Hyperthyroidism usually causes tachycardia, weight loss, and nervousness. On the other hand, hypothyroidism may cause lethargy, weight gain, and cold intolerance.

Retrieved from https://terrainwellness.com/symptoms-of-hashimotos-flare-up/ on 29th April 2022

Thyroid Disease Risk Factors

  • family history of thyroid disease
  • medical conditions eg. type 1 diabetes and rheumatoid arthritis)
  • high iodine-containing medication eg. amiodarone
  • increased age
  • past thyroidectomy
  • past radiation

Hyperthyroidism Causes

  • Graves’ Disease
  • Nodules
  • Thyroiditis
  • Excessive iodine intake

Symptoms

  • anxiety
  • irritability
  • nervousness
  • heat sensitivity
  • insomnia
  • vision problems
  • eye irritation
  • goitre
  • tremors.
  • irregular periods
  • period cessation
  • shortness of breath – patient has high metabolism, muscle wasting, leading to exhaustion and fatigue, all of which can cause shortness of breath
  • weight loss – imbalanced nutrition due to high metabolic rate (adequate food intake needs to be ensured)
  • muscle weakness – in case of inadequate food intake, if no carbs or glucose are available to be broken down, the body turns to protein breakdown, leading to muscle wasting

Hypothyroidism Causes

  • Thyroiditis
  • Hashimoto’s Thyroiditis
  • Post-Partum Thyroiditis (usually temporary)
  • Iodine Deficiency
  • Non-Functioning Thyroid Gland

Symptoms

  • cold sensitivity
  • memory problems
  • voice hoarseness
  • hair dryness and coarseness
  • fatigue
  • weight gain
  • frequent and heavy periods

Thyroid Disease Diagnostic Tests

  • TFTs (TSH, T4 and T3 levels) – to check the amount of thyroid stimulating hormone (TSH) and circulating thyroid hormones in serum, so thyroid gland’s thyroid hormone production and regulation ability is assessed
  • CBC – to check amount of red blood cells in the blood (to rule out anaemia)
  • Renal Profile – to determine the kidneys’ health by evaluating parameters such as proteins, electrolytes, and minerals

Subclinical Thyroid Dysfunction

Subclinical Thyroid Dysfunction is a biochemical diagnosis in which TSH levels are outside the reference range, and circulating T4 and T3 are within the reference range.

Subclinical Thyroid Dysfunction is most commonly detected incidentally. However, in certain cases, individuals may exhibit symptoms of hypothyroidism or hyperthyroidism. Studies related to long-term consequences of subclinical thyroid dysfunction indicate increased cardiovascular morbidity and mortality, increased risk of osteoporosis, and possible links to dementia.

Thyroid Disease Patient Education – Based On NICE Guidelines (2019)

Ensure that information is presented to facilitate shared decision making…

Explain to people with thyroid disease who need treatment, and their family or carers…that:

– Thyroid disease usually responds well to treatment.

– The goal of treatment is to alleviate symptoms and align thyroid function tests within or close to the reference range.

– People may feel well even when their thyroid function tests are outside the reference range.

– Even when there are no symptoms, treatment may be advised to reduce the risk of long-term complications.

– Even when thyroid function tests are within the reference range, changes to treatment may improve symptoms for some people.

– Symptoms may lag behind treatment changes for several weeks to months.

– Day-to-day changes in unexplained symptoms are unlikely to be due to underlying thyroid disease because the body has a large reservoir of thyroxine.

Provide people with thyroid disease, and their family or carers…with written and verbal information on:

– their underlying condition, including the role and function of the thyroid gland and what the thyroid function tests mean

– risks of over-and under-treatment

-their medicines

-need for and frequency of monitoring

– when to seek advice from a healthcare professional

– how thyroid disease and medicines may affect pregnancy and fertility

Provide people with hypothyroidism, and their family…with written and verbal information on:

– possible drug interactions of thyroid hormone replacements, including interactions with over-the-counter medicines

– how and when to take levothyroxine

NICE Guidelines, 2019

Patients with thyroid disease need to have a clear understanding on the disease, treatment goals, and connection between thyroid function tests and symptoms. Medication (Levothyroxine) is frequently taken incorrectly, possibly leading to suboptimal treatment.

Patient information and support on thyroid disease help patients make informed decisions on the management of their condition.

A complete drug history of the patient helps determine if Levothyroxine may interfere with other medications currently being taken, in which case, the patient may be recommended to take Levothyroxine earlier or half hour before food and other medications.

Review of other drug intake should be made so if needed, changes may be made to drug prescription. Example: Iodine may cause toxicity problems with the thyroid gland and may lead to hypothyroidism. Example: Lithium use blocks thyroid hormone production.

The patient needs to be made aware that any side effects experienced may be due to thyroid disease, and that, if kept under control, such side effects may be reduced. Constipation, which is one of the side effects of hypothyroidism, may subside following regular use of Levothyroxine. However, if it persists, increasing high fibre intake and more fluids should help further. Movicol may also be prescribed to help with constipation (if other methods fail to help).

Regular exercise needs to be encouraged, starting slowly, and increasing gradually. This is because patients with thyroid disease such as hypothyroidism tend to gain weight. If necessary, patient may be referred to a dietitian.

Medication compliance is very important with regards to Levothyroxine. The patient needs to be educated about the condition – that it is a lifelong condition which needs to be controlled by medication. It is a chronic disease. Thus, Levothyroxine should not be stopped, even if patient feels well.

Patient should be encouraged to attend all follow-ups so as to ensure that the right dose has been prescribed. It may take a couple of follow-ups until the right dose is achieved. The patient should be instructed that in case of palpitations, chest pain, and tachycardia, contact should be made with clinician so as to ensure she is not going into hyperthyroidism instead.

References

Cleveland Clinic (2020). Thyroid Disease: Causes, Symptoms, Risk Factors, Testing & Treatment. Retrieved from https://my.clevelandclinic.org/health/diseases/8541-thyroid-disease on 5th May 2022

NICE Guidelines (2019). Thyroid Disease: assessment and management. Retrieved from https://www.nice.org.uk/guidance/ng145 on 5th May 2022


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Thyroidectomy Perioperative Nursing Care

The thyroid gland plays a major role in the metabolism, growth and development of the human body, regulating body functions by constantly releasing a steady amount of thyroid hormones into the bloodstream. At times however, an individual may require a thyroidectomy, which is the surgical removal of all or part of the thyroid gland. This may happen due to thyroid-related conditions such as Goitre and Carcinomas.

Hypothyroidism vs Hyperthyroidism

In hypothyroidism, the thyroid gland is underactive, hence it doesn’t produce enough thyroid hormone. On the other hand, in hyperthyroidism, the thyroid gland is overactive, hence it produces too much thyroid hormone.

Thyroidectomy Perioperative Nursing Care
Retrieved from https://terrainwellness.com/symptoms-of-hashimotos-flare-up/ on 29th April 2022

Thyroidectomy Indications

Goitre

A goitre a.k.a. goiter refers to swelling of the thyroid gland which causes a lump located at the front of the neck which moves up and down with swallowing. Nodules are lumps located within the thyroid gland.

  • Solitary Nodular Goitre (single swelling) – most commonly benign, solitary nodular goitres are often left untreated. If upon examination cancer is not excluded, surgery is usually recommended. An overactive nodule a.k.a. hot nodule can be treated by pharmacological medication, radioactive iodine treatment, or surgery.
  • Multi-Nodular Goitre (multiple swellings) – common multiple swellings which usually do not require surgery unless breathing and/or swallowing become compromised, or in case of rapidly growing nodules, or the individual prefers to undergo surgery for aesthetic purposes (unsightly goitre).
Thyroidectomy Perioperative Nursing Care
Retrieved from https://my.clevelandclinic.org/health/diseases/13121-thyroid-nodule on 29th April 2022
Thyroidectomy Perioperative Nursing Care
Right thyroid nodule, multinodular goiter. Contributed by Ahmet Selรงuk Can, MD. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK535422/figure/article-30147.image.f3/ on 29th April 2022

Carcinoma

Thyroid cancer is a rare type of cancer affecting the thyroid gland. Types of thyroid cancers include:

  • papillary carcinoma โ€“ the most common type, affecting mostly females under 40; papillary carcinomas appear as irregular solid or cystic masses or nodules
  • follicular carcinoma โ€“ affecting mostly middle-aged females, these malignant epithelial tumors account for about 15% of malignant thyroid tumors
  • rare carcinomas – include thyroid teratomas, lymphomas, and squamous cell carcinomas.
Retrieved from https://basicmedicalkey.com/cancer-treatment-and-chemotherapy/ on 21st June 2022
Thyroidectomy Perioperative Nursing Care
Retrieved from https://www.cancer.gov/types/thyroid/patient/thyroid-treatment-pdq on 29th April 2022

Thyroidectomy Types

  • Hemi-Thyroidectomy – removal of half of the thyroid gland
  • Lobectomy – removal of either the right or the left thyroid gland lobe, commonly done in the case of solitary goitre
  • Total Thyroidectomy – removal of the whole thyroid gland, commonly done in cases of malignant thyroid tumors
  • Subtotal Thyroidectomy – removal of almost whole thyroid gland, commonly done in multi-nodular goitre (some thyroid tissue surrounding one parathyroid gland is preserved)
  • Near-Total Thyroidectomy – removal of almost whole thyroid gland, commonly done in multi-nodular goitre (some thyroid tissue surrounding one parathyroid gland is preserved)
  • Isthmusectomy – removal of the thyroid isthmus
Retrieved from https://cancer.ca/en/cancer-information/cancer-types/thyroid/treatment/surgery on 5th May 2022

Thyroidectomy Perioperative Nursing Care

Thyroidectomy Preoperative Care

BLOOD INVESTIGATIONS:

  • CBC
  • Urea, Electrolytes, & Creatinine
  • T3, T4, & TSH (Thyroid Stimulating Hormone)

SCANS:

  • Thyroid Gland ultrasound scan
  • Radio-Iodine Thyroid Scan
  • Neck X-ray
  • Chest X-ray

OTHER INVESTIGATIONS:

  • FNAC (Fine Needle Apiration Cytology) of thyroid nodule, if palpable
  • Indirect Laryngoscopy for pre-operative assessment of vocal cords functioning

CARE:

  • patient reassurance through answering of any questions in relation to surgery so as to help reduce patient anxiety and fear; this also helps in acquiring informed consent
  • patient education regarding neck support in preparation for post-operative self-care
  • administration of anti-thyroid medication eg. Methimazole to promote a euthyroid (normal thyroid function) state
  • preparation of Potassium Iodide (Iodine) which helps to decrease thyroid gland vascularity, thus reducing risk for haemorrhage
  • avoid prophylactic antibiotic administration in such a clean elective surgery unless indicated

Thyroidectomy Postoperative Care

PATIENT CARE ON DAY OF SURGERY:

  • monitor patient’s vital signs and document accordingly
  • keep patient NBM (nil-by-mouth)
  • administer between 2.5l-3l of supplemental IV fluid
  • administer analgesics as prescribed to reduce severe post-operative pain
  • in case of excessive blood loss during surgery, blood transfusion may be required

PATIENT CARE FROM DAY 2:

  • encourage initial sips of clear fluid; move on to free fluids, to a soft diet, and finally to a normal diet once each phase is tolerated
  • maintain vital signs monitoring – temperature rise following 3rd day of surgery indicates infection
  • monitor surgical site for signs of infection; change initial dressing after 48-72hrs following surgery (unless it’s soaked beforehand, in which case should be changed earlier); use dry dressings every alternate day if suture line is clean and dry; removal of sutures is recommended for the 5th day post-op to avoid scarring as much as possible
  • monitor daily output from Redivac Drain – remove drain after 48 hours OR when drainage is reduced to a few milliliters in a 24hr period
  • keep on administering prescribed analgesics, monitoring their effectiveness and taking necessary measures in case of inefficacy

Redivac Drain

Thyroidectomy Complications

  • haemorrhage – assess surgical wound area for drainage, monitor blood pressure and pulse to notice possible hypovolaemic shock earlier on; risk of haemorrhage is at its peak in the first 24 hours post-op
  • respiratory distress – assess respiratory rate, rhythm, depth, and strength; prepare suction equipment, oxygen, and tracheostomy set at hand since possible haemorrhage and oedema may result in tracheal compression
  • wound infection
  • voice hoarseness and aphonia (total vocal cord paralysis due to nerve damage which causes sounds to come out as just whispers) – assess speaking tone and ability; hoarseness, which eventually subsides, happens due to oedema or endotracheal tube used during surgery
  • hypocalcemic tetany (low calcium levels in the blood caused by accidental parathyroid glands removal in total thyroidectomy) – this complication may occur in up to 7 days post-op; signs and symptoms include tingling of toes, fingers, and lips; prepare calcium gluconate or calcium chloride in case it’s needed for IV use

Further Related Information

Graves’ Disease

Graves’ disease is an immune system disorder that causes overproduction of thyroid hormones a.k.a. hyperthyroidism. Signs and symptoms of Graves’ disease can be wide ranging.

Thyroidectomy Perioperative Nursing Care
Retrieved from https://homeopathyplus.com/graves-disease-homeopathy/ on 30th April 2022

Hashimoto’s Disease

Hashimoto’s Thyroiditis a.k.a. Hashimoto’s Disease is an autoimmune disease that causes the body to produce antibodies which attack thyroid cells, leading to the under-production of the thyroid hormone. Symptoms of Hashimoto’s Disease may include goitre, lethargy, weight gain, and muscle weakness.

Retrieved from https://www.netmeds.com/health-library/post/hashimotos-disease-causes-symptoms-and-treatment on 30th April 2022

Thyroid Storm

Thyroid storm a.k.a. thyrotoxic crisis is an acute, life-threatening, hypermetabolic state caused by excessive release of thyroid hormones in individuals with thyrotoxicosis. Thyroid storm may be the initial presentation of thyrotoxicosis in undiagnosed paediatric patients, especially neonates.

Retrieved from https://m.facebook.com/permalink.php?story_fbid=1866113336780022&id=777683445623022&locale2=ja_JP on 30th April 2022

Myxedema Coma

Myxedema coma, which is considered to be a medical emergency with a high mortality rate, is defined as severe hypothyroidism that causes decreased mental status, hypothermia, and other organs to slow down their functions.

Retrieved from https://healthjade.net/myxedema-coma/ on 30th April 2022

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