Thyroidectomy Perioperative Nursing Care

The thyroid gland plays a major role in the metabolism, growth and development of the human body, regulating body functions by constantly releasing a steady amount of thyroid hormones into the bloodstream. At times however, an individual may require a thyroidectomy, which is the surgical removal of all or part of the thyroid gland. This may happen due to thyroid-related conditions such as Goitre and Carcinomas.

Hypothyroidism vs Hyperthyroidism

In hypothyroidism, the thyroid gland is underactive, hence it doesn’t produce enough thyroid hormone. On the other hand, in hyperthyroidism, the thyroid gland is overactive, hence it produces too much thyroid hormone.

Thyroidectomy Perioperative Nursing Care
Retrieved from https://terrainwellness.com/symptoms-of-hashimotos-flare-up/ on 29th April 2022

Thyroidectomy Indications

Goitre

A goitre a.k.a. goiter refers to swelling of the thyroid gland which causes a lump located at the front of the neck which moves up and down with swallowing. Nodules are lumps located within the thyroid gland.

  • Solitary Nodular Goitre (single swelling) – most commonly benign, solitary nodular goitres are often left untreated. If upon examination cancer is not excluded, surgery is usually recommended. An overactive nodule a.k.a. hot nodule can be treated by pharmacological medication, radioactive iodine treatment, or surgery.
  • Multi-Nodular Goitre (multiple swellings) – common multiple swellings which usually do not require surgery unless breathing and/or swallowing become compromised, or in case of rapidly growing nodules, or the individual prefers to undergo surgery for aesthetic purposes (unsightly goitre).
Thyroidectomy Perioperative Nursing Care
Retrieved from https://my.clevelandclinic.org/health/diseases/13121-thyroid-nodule on 29th April 2022
Thyroidectomy Perioperative Nursing Care
Right thyroid nodule, multinodular goiter. Contributed by Ahmet Selçuk Can, MD. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK535422/figure/article-30147.image.f3/ on 29th April 2022

Carcinoma

Thyroid cancer is a rare type of cancer affecting the thyroid gland. Types of thyroid cancers include:

  • papillary carcinoma â€“ the most common type, affecting mostly females under 40; papillary carcinomas appear as irregular solid or cystic masses or nodules
  • follicular carcinoma – affecting mostly middle-aged females, these malignant epithelial tumors account for about 15% of malignant thyroid tumors
  • rare carcinomas – include thyroid teratomas, lymphomas, and squamous cell carcinomas.
Retrieved from https://basicmedicalkey.com/cancer-treatment-and-chemotherapy/ on 21st June 2022
Thyroidectomy Perioperative Nursing Care
Retrieved from https://www.cancer.gov/types/thyroid/patient/thyroid-treatment-pdq on 29th April 2022

Thyroidectomy Types

  • Hemi-Thyroidectomy – removal of half of the thyroid gland
  • Lobectomy – removal of either the right or the left thyroid gland lobe, commonly done in the case of solitary goitre
  • Total Thyroidectomy – removal of the whole thyroid gland, commonly done in cases of malignant thyroid tumors
  • Subtotal Thyroidectomy – removal of almost whole thyroid gland, commonly done in multi-nodular goitre (some thyroid tissue surrounding one parathyroid gland is preserved)
  • Near-Total Thyroidectomy – removal of almost whole thyroid gland, commonly done in multi-nodular goitre (some thyroid tissue surrounding one parathyroid gland is preserved)
  • Isthmusectomy – removal of the thyroid isthmus
Retrieved from https://cancer.ca/en/cancer-information/cancer-types/thyroid/treatment/surgery on 5th May 2022

Thyroidectomy Perioperative Nursing Care

Thyroidectomy Preoperative Care

BLOOD INVESTIGATIONS:

  • CBC
  • Urea, Electrolytes, & Creatinine
  • T3, T4, & TSH (Thyroid Stimulating Hormone)

SCANS:

  • Thyroid Gland ultrasound scan
  • Radio-Iodine Thyroid Scan
  • Neck X-ray
  • Chest X-ray

OTHER INVESTIGATIONS:

  • FNAC (Fine Needle Apiration Cytology) of thyroid nodule, if palpable
  • Indirect Laryngoscopy for pre-operative assessment of vocal cords functioning

CARE:

  • patient reassurance through answering of any questions in relation to surgery so as to help reduce patient anxiety and fear; this also helps in acquiring informed consent
  • patient education regarding neck support in preparation for post-operative self-care
  • administration of anti-thyroid medication eg. Methimazole to promote a euthyroid (normal thyroid function) state
  • preparation of Potassium Iodide (Iodine) which helps to decrease thyroid gland vascularity, thus reducing risk for haemorrhage
  • avoid prophylactic antibiotic administration in such a clean elective surgery unless indicated

Thyroidectomy Postoperative Care

PATIENT CARE ON DAY OF SURGERY:

  • monitor patient’s vital signs and document accordingly
  • keep patient NBM (nil-by-mouth)
  • administer between 2.5l-3l of supplemental IV fluid
  • administer analgesics as prescribed to reduce severe post-operative pain
  • in case of excessive blood loss during surgery, blood transfusion may be required

PATIENT CARE FROM DAY 2:

  • encourage initial sips of clear fluid; move on to free fluids, to a soft diet, and finally to a normal diet once each phase is tolerated
  • maintain vital signs monitoring – temperature rise following 3rd day of surgery indicates infection
  • monitor surgical site for signs of infection; change initial dressing after 48-72hrs following surgery (unless it’s soaked beforehand, in which case should be changed earlier); use dry dressings every alternate day if suture line is clean and dry; removal of sutures is recommended for the 5th day post-op to avoid scarring as much as possible
  • monitor daily output from Redivac Drain – remove drain after 48 hours OR when drainage is reduced to a few milliliters in a 24hr period
  • keep on administering prescribed analgesics, monitoring their effectiveness and taking necessary measures in case of inefficacy

Redivac Drain

Thyroidectomy Complications

  • haemorrhage – assess surgical wound area for drainage, monitor blood pressure and pulse to notice possible hypovolaemic shock earlier on; risk of haemorrhage is at its peak in the first 24 hours post-op
  • respiratory distress – assess respiratory rate, rhythm, depth, and strength; prepare suction equipment, oxygen, and tracheostomy set at hand since possible haemorrhage and oedema may result in tracheal compression
  • wound infection
  • voice hoarseness and aphonia (total vocal cord paralysis due to nerve damage which causes sounds to come out as just whispers) – assess speaking tone and ability; hoarseness, which eventually subsides, happens due to oedema or endotracheal tube used during surgery
  • hypocalcemic tetany (low calcium levels in the blood caused by accidental parathyroid glands removal in total thyroidectomy) – this complication may occur in up to 7 days post-op; signs and symptoms include tingling of toes, fingers, and lips; prepare calcium gluconate or calcium chloride in case it’s needed for IV use

Further Related Information

Graves’ Disease

Graves’ disease is an immune system disorder that causes overproduction of thyroid hormones a.k.a. hyperthyroidism. Signs and symptoms of Graves’ disease can be wide ranging.

Thyroidectomy Perioperative Nursing Care
Retrieved from https://homeopathyplus.com/graves-disease-homeopathy/ on 30th April 2022

Hashimoto’s Disease

Hashimoto’s Thyroiditis a.k.a. Hashimoto’s Disease is an autoimmune disease that causes the body to produce antibodies which attack thyroid cells, leading to the under-production of the thyroid hormone. Symptoms of Hashimoto’s Disease may include goitre, lethargy, weight gain, and muscle weakness.

Retrieved from https://www.netmeds.com/health-library/post/hashimotos-disease-causes-symptoms-and-treatment on 30th April 2022

Thyroid Storm

Thyroid storm a.k.a. thyrotoxic crisis is an acute, life-threatening, hypermetabolic state caused by excessive release of thyroid hormones in individuals with thyrotoxicosis. Thyroid storm may be the initial presentation of thyrotoxicosis in undiagnosed paediatric patients, especially neonates.

Retrieved from https://m.facebook.com/permalink.php?story_fbid=1866113336780022&id=777683445623022&locale2=ja_JP on 30th April 2022

Myxedema Coma

Myxedema coma, which is considered to be a medical emergency with a high mortality rate, is defined as severe hypothyroidism that causes decreased mental status, hypothermia, and other organs to slow down their functions.

Retrieved from https://healthjade.net/myxedema-coma/ on 30th April 2022

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Thyroid Gland Anatomy and Physiology

The thyroid gland is situated just below the larynx, with its right and left lateral lobes lying on either side of the trachea, connected together by the isthmus. It plays a major role in the metabolism, growth and development of the human body, regulating body functions by constantly releasing a steady amount of thyroid hormones into the bloodstream. It receives a rich blood supply of about 80 to 120ml per minute.

Thyroid Gland Anatomy and Physiology
Retrieved from http://www.aboutcancer.com/thyroid_anatomy.htm on 27th April 2022

Thyroid Gland Histology

The thyroid gland is composed of spherical sacs called thyroid follicles which are covered by a wall made up of Follicular Cells and Parafollicular Cells a.k.a. C Cells.

  • Follicular Cells produce thyroxine (T4) and triiodothyronine (T3). Whilst T4 is usually produced in greater quantities than T3, T3 is up to 4 times more potent than T4. Additionally, about a third of T3 is converted to T4 within peripheral tissues, especially within the lungs and the liver.
  • Parafollicular Cells produce calcitonin (CT).
Thyroid Gland Anatomy and Physiology
Retrieved from https://slideplayer.com/slide/13219076/ on 27th April 2022

Thyroid Hormone Formation, Storage & Release

The thyroid gland is the only endocrine gland that stores its hormonal products in large quantities, eventually releasing them steadily over time. Thyroid hormone formation, storage and release occurs through the following process:

  1. Iodide Trapping – iodide ions are actively transported from the blood to the follicular cells
  2. Thyroglobulin Synthesis – during iodide ion trapping, follicular cells synthesise the glycoprotein Thyroglobulin (TGB) which is released into the thyroid follicle lumen by exocytosis, resulting in colloid accumulation within the lumen and Tyrosine (amino acids) iodination in TGB
  3. Iodide Oxidation – iodide ions bind to TGB following oxidation; simultaneously, iodine is formed by the action of peroxidase
  4. Tyrosine Iodination – formed iodine reacts with tyrosine in the colloid; one iodine atom binding forms monoiodotyrosine (T1); a second iodine atom binding produces diiodotyrosine (T2)
  5. T1 and T2 Coupling – T1 and T2 join and form thyroid hormones
  6. Colloid Pinocytosis & Digestion – colloid droplets re-enter the follicular cells though pinocytosis, and then merge with lysosomes in the follicular cells; lysozyme breaks down TGB, and then produce T3 and T4 molecules
  7. Thyroid Hormone Secretion – lipid-soluble T3 and T4 diffuse through the plasma membrane into the interstitial fluid, and then into the blood; T4 is secreted in larger quantities than T3, yet T3 is much more potent than T4
  8. Transport into Blood – Thyroxine-Binding Globulin (TBG) which is a transport protein found within the blood plasma combine with both T3 and T4 and are carried around in the body within the blood; when T4 enters a cell, most of it is converted to T3 following removal of one iodine

NOTE: Iodine supplements may be given to pregnant women and for compensation of hypothyroidism.

Thyroid Gland Anatomy and Physiology
Retrieved from https://www.pinterest.com/pin/395261304797063744/ on 27th April 2022

Thyroid Hormone Regulation

Thyroid hormone secretion is stimulated by various factors…

hormone regulation
Retrieved from https://quizlet.com/502370009/phys_block-8_-endo-5-6-flash-cards/ on 27th April 2022

Calcitonin (CT)

Calcitonin, which is produced by the parafollicular cells of the thyroid gland, is involved in the homeostasis of blood calcium level:

  • Calcitonin inhibits bone breakdown and promotes bone calcium absorption
  • Calcitonin is used in the treatment of post-menopausal osteoporosis along with calcium and vitamin dietary intake
  • Calcitonin secretion is controlled via a negative feedback system
Calcitonin
Retrieved from https://healthjade.net/calcitonin/ on 27th April 2022

NOTE: Diarrhoea is a possible sign of increased thyroid hormone. Similarly, constipation is a possible sign of underactive thyroid.


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