Electrical Signals In Neurons

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When talking about electrical signals in neurons we are referring to action potentials that transmit information from one neuron to another.

Neurons are said to be electrically excitable since upon sensing factors from the surrounding environment, excitability helps in providing impulses. There are 2 types of electrical signals in neurons:

GRADED POTENTIALS – these electrical signals, which happen when a stimulus causes ligand-gated or mechanically-gated channels to open or close in an excitable cell’s plasma membrane, are active only over short distances within the body. Such a graded potential is featured as a small deviation from the membrane potential, making it either more polarised (hyperpolarising graded potential) or less polarised (depolarising graded potential).

Electrical Signals In Neurons
Retrieved from https://content.byui.edu/file/a236934c-3c60-4fe9-90aa-d343b3e3a640/1/module5/readings/graded_potential.html on 5th November 2021

ACTION POTENTIALS – these electrical signals are active for both short and long distances within the body. During action potentials, 2 types of voltage-gated channels open and close: Na+ channels open and let Na+ rush in the cell, causing depolarisation, while K+ channels open, causing K+ to flow out, causing repolarisation.

Electrical Signals In Neurons
Retrieved from https://www.clutchprep.com/physiology/practice-problems/140705/place-the-following-statements-in-the-correct-order-for-an-action-potential-to-b on 5th November 2021

Both graded potentials and action potentials are produced thanks to the plasma membrane’s 2 main features:

  • Ion Channels
  • Resting Membrane Potential
Electrical Signals In Neurons
Electrical Signals In Neurons
Retrieved from https://www.slideshare.net/SajinSali/membrane-physiology-30444693 on 5th November 2021
Electrical Signals In Neurons
Retrieved from https://slideplayer.com/slide/10147661/ on 5th November 2021

Impulse Generation

Retrieved from https://www.pinterest.com/pin/665477282413908619/ on 5th November 2021
Retrieved from http://loretocollegebiology.weebly.com/synapses.html on 5th November 2021

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Nervous System Introduction For Nursing Students

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The nervous system is the body’s control centre and communications network – it is the main controlling, regulatory and communicating system within the body. It is responsible for all mental activity, including thought, learning and memory.

The nervous system works in conjunction with the endocrine system to regulate and maintain homeostasis by picking up information about the external and internal environment through its receptors.

The 3 Functions of the Human Nervous System

  1. SENSORY – senses changes within the body as well as within the outside environment
  2. INTEGRATIVE – is able to interpret and understand changes
  3. MOTOR – provides a responsive action to its interpretation of sensed changes through muscular contractions or glandular secretions
nervous system
Retrieved from https://www.austincc.edu/apreview/PhysText/CNS.html on 29th October 2021

The 2 Principal Divisions Emerging From The Nervous System

nervous system
Retrieved from https://ib.bioninja.com.au/options/option-a-neurobiology-and/a2-the-human-brain/autonomic-control.html on 29th October 2021

The Central Nervous System

  • Consists of the brain and the spinal cord
  • Controls the entire nervous system
  • Responsible for thoughts, emotions and memories
  • Integrates and correlates all kinds of incoming sensory information thanks to receptors that relay the information
  • Triggers nerve impulses to stimulate muscle contractions and gland secretions
Retrieved from https://faculty.etsu.edu/forsman/CentralNervousSystemCompleteDiagram.htm on 29th October 2021

The Peripheral Nervous System

  • Made up of various nerve processes which connect the brain and spinal cord through receptors, muscles and glands
  • Divides into the Afferent System (nerve cells ‘afferent neurones’ that convey information from peripheral receptors to the CNS) and the Efferent System (nerve cells ‘efferent neurones’ that convey information from the CNS to muscles and glands)
  • The Efferent System subdivides into the Somatic Nervous System (voluntary effect by efferent neurones conducting impulses from the CNS to the skeletal muscle tissue) and the Autonomic Nervous System (involuntary effect by efferent neurones conveying impulses from the CNS to smooth muscle tissue, cardiac muscle tissue and glands)
nervous system
Retrieved from https://en.wikipedia.org/wiki/Central_nervous_system on 30th October 2021

Nervous Tissue Histology

Nervous tissue consists of 2 types of cells:

NEURONS:

  • Contain well developed excitability and conductivity properties that have the ability to respond to adequate stimulus by initiating an action potential that reaches to the cell’s other end, relaying the action potential to another
  • Responsible for the receiving and transmitting of nerve impulses such as sensing, thinking, remembering, controlling muscle activity, and regulating glandular secretions
  • Is made up of 3 parts, namely the CELL BODY, which contains a nucleus surrounded by cytoplasm with all organelles and nissl bodies; DENDRITES, responsible for receiving or input; and the AXON, which propagates nerve impulses towards another neuron, muscle fibre or gland cell
nervous system
Retrieved from https://www.sciencefacts.net/parts-of-a-neuron.html on 30th October 2021
Neuron Types

BIPOLAR NEURON (a.k.a. Interneuron)

  • One main dendrite
  • One axon
  • Commonly found in the retina of the eye, the inner ear and the brain’s olfactory area

UNIPOLAR NEURON (a.k.a. Sensory Neuron)

  • Begins in the embryo as bipolar neurons
  • Dendrites extend into the periphery from the axon
  • Axon branch extending into the CNS ends in synaptic end bulbs

MULTIPOLAR NEURON (a.k.a. Motor Neuron)

  • Several dendrites
  • One axon
  • Commonly found in the brain and the spinal cord
Retrieved from https://www.researchgate.net/figure/Basic-Neuron-types-Most-neurons-are-collected-into-packages-of-one-sort-or-another_fig4_293333043 on 30th October 2021

NEUROGLIA:

  • Smaller in size than neurons
  • Constitute half the CNS volume
  • Do not generate or propagate action potentials
  • Have the ability to multiply and divide within the mature nervous system
  • Support, nourish and protect neurons
  • Maintain homeostasis in the interstitial fluid that surrounds the neurons

Nervous System Cell Types

Retrieved from https://www.pinterest.com/pin/545357836125394127/ on 30th October 2021

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Pressure Ulcers Classification, Risk Assessment and Nursing Care

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Pressure ulcers, also known as decubitus ulcer, decubiti, bedsores, pressure sores, pressure injuries, and pressure necrosis, are basically ulcers caused by pressure. Similarly, pressure ulcers can also develop following shearing and friction.

Intrinsic & Extrinsic Causative Factors Leading To Pressure Ulcers

Intrinsic Factors:

  • Age
  • Malnutrition
  • Chronic Illness
  • Ischaemia
  • Tissue Tolerance – how much the skin and its supporting structures are able to redistribute pressure

Extrinsic Factors:

  • Pressure over bone-prominent areas
  • Shearing forces eg. patient slides down the bed
  • Friction – rubbing of epithelial layer of the skin against another surface

Capillary Pressure

Blood pressure at the arterial end of the capillaries is around 32mmHg, dropping to 10mmHg at the venous end.

Average mean capillary pressure is around 17mmHg. External pressures exceeding this amount is set to cause capillary obstruction.

Tissues dependent on these capillaries become deprived of blood supply, and eventually, these ischaemic tissues die.

  • Hyperemia – pressure applied for up to 30 minutes (resolves after an hour)
  • Ischaemia – unrelieved pressure for up to 6 hours (may require up to 36 hours to resolve)
  • Necrosis – develops after 6 hours of unrelieved pressure with microvasculature collapse and thrombosis
  • Ulceration – presents within 2 weeks after necrosis

Pressure Sores Etiology

pressure ulcers
Retrieved from https://www.aboutkidshealth.ca/Article?contentid=772&language=English on 28th June 2022
pressure ulcers
Retrieved from https://owlcation.com/stem/Pressure-Ulcers on 28th June 2022
Retrieved from https://thehearingaidpodcasts.org.uk/episode-3-3-preventing-pressure-ulcers/ on 28th June 2022

Avoidable Pressure Ulcers

Pressure ulcers development can be avoided if the healthcare provider follows these 4 steps:

  1. EVALUATE the patient’s clinical condition and perform a pressure ulcer risk assessment
  2. DEFINE & IMPLEMENT interventions based on the patient’s individual needs and goals
  3. MONITOR & EVALUATE how the patient is responding to the interventions
  4. REVISE interventions as / if necessary

Pressure Ulcers Risk Assessment

  • Bed-bound and chair-bound individuals should be considered as being at risk for pressure ulcers
  • Assess higher-risk individuals at admission. Keep assessing at regular intervals as well as with any change in condition.
  • Assess patients in acute care on admission and at least every 24 hours, increasing assessment times in case of any change in condition
  • Assess patients receiving long term care on admission, followed by weekly assessments for four weeks, spacing to quarterly. Increase frequency of assessment with any change in patient’s condition
  • Assess patients receiving community care at home on admission and at every visit
  • Consider all risk factors, including decreased mental status, exposure to moisture, incontinence, device-related pressure, friction and shearing, immobility and inactivity, as well as lack of proper nutrition
  • Based upon the noted individualised risk assessment, guide patient on related preventative measures and modify or refer to any needed multi-disciplinary team services when necessary
  • Document risk assessment and work on the implementation of the individualised prevention and care plan

The Braden Risk Assessment Scale

Waterlow Pressure Ulcer Prevention Assessment

Pressure Injury Staging

Pressure injury staging requires the following considerations:

  • history
  • visual observation and palpation
  • full body (head to toe) skin assessment – consider patient’s position

Following the above, the following is required:

  1. clean the pressure ulcer
  2. note the deepest anatomic type of soft tissue that has been damaged

Mucosal Membrane Pressure Injuries

Mucosal membrane pressure injury is injury on mucous membranes on which medical devices had to be used. Pressure applied to mucous membranes can cause ischaemia, which then turns into ulceration. Such injuries cannot be staged.

Mucosal membrane pressure injury examples include pressure ulcers which develop on the nasal mucosa from pressure exerted by nasal prongs, and pressure ulcers which develop on the inner lip due to pressure exerted by an endotracheal tube.

Device-Related Pressure Injuries

Device-related pressure injuries are injuries incurred following the use of medical devices applied for diagnostic or therapeutic purposes (excluding devices that come into contact with the mucosal membranes, as mentioned above). Staging of such injuries should be done using the normal staging system.

Pressure Ulcer Classification & Wound Management Considerations

pressure ulcers nursing care
Retrieved from https://www.pinterest.fr/pin/299137600253202126/?amp_client_id=CLIENT_ID(_)&mweb_unauth_id={{default.session}}&simplified=true on 26th October 2021

STAGE 1:

  • no visible wound
  • use a dressing just to cover for protection if necessary

STAGE 2:

  • primary non-adherent dressing / antimicrobial dressing for susceptible patients
  • secondary absorptive dressing based on exhudate amount

STAGE 3:

  • where depth of wound is minimal follow directions for stage 2 (above)

STAGE 4:

  • where depth is very deep with dead spaces, manage exhudate and infection, and consider antimicrobials in susceptible patients

UNSTAGEABLE:

  • debride if indicated
  • if debridement is not indicated, minimise risk of infection by using non-adherent antimicrobial dressing which is ideal for dry wounds

Diagnosis of Pressure Ulcers

Pressure ulcers are sometimes confused with wounds caused by moisture, such as the development of wounds on an incontinent person left with a soiled diaper for a long time. Proper diagnosis is of utmost importance since prevention and treatment varies between pressure ulcers and moisture associated skin damage (MASD).

Retrieved from https://www.nursingtimes.net/clinical-archive/tissue-viability/incontinence-associated-dermatitis-3-systems-for-reporting-skin-damage-27-04-2020/ on 27th October 2021
Retrieved from https://ar.pinterest.com/pin/618259855069276004/ on 27th October 2021

Tunneling and Undermining

Effective Wound Care Process

Negative Pressure Wound Therapy

Preventing Pressure Ulcers

The Rule of 300

SSkin Care Bundle

Retrieved from https://www.vernacare.com/news-hub/blog/posts/2018/november/feeling-the-pressure-our-vernacare-skin-care-guide/ on 27th October 2021

Patient Skin Assessment

  1. At least once daily (or as suggested further above), perform a head-to-toe skin assessment. Note in particular common sites of pressure ulcer formation, such as the sacrum, ischium, trochanters, heels, elbows, and the back of the head
  2. Provide individualised care when it comes to bathing frequency and cleansing agents. Mild cleansing agents are preferred. Do not use hot water and do not towel-rub eccessively so as to avoid damaging the skin. Follow bathing with the use of an appropriate lotion or moisturising agent
  3. In patients with incontinence, cleanse skin following soiling and apply a topical barrier to protect the area. Aldanex is an ideal barrier product that helps prevent, protect and promote healing. A pouching system or collection device for faeces can also be considered so as to provide further protection to the skin
  4. Use moisturising agents for dry skin and reduce environmental risk factors such as low humidity and cold air. Do not massage bony prominences

Positioning

  1. Encourage mobility for patients able to move
  2. Reposition bed-bound patients at least every 2 hours; make use of lifting devices during transferring and repositioning of patients
  3. Reposition chair/wheelchair-bound patients every 1 hour; consider positional alignment, distribution of weight, balance and stability, and pressure redistribution
  4. Use pillows or foam wedges to protect bony prominences from direct contact with each other
  5. Follow a written repositioning schedule – if none is available, be proactive!
  6. Use pressure-redistributing mattresses and chair cushion surfaces for high-risk patients; DO NOT use donut-type devices and sheepskin for pressure redistribution!
  7. Pressure-redistributing devices should also be used in the operating room for high-risk individuals

Nutrition & Hydration

  1. Identify patient’s nutrition needs in relation to protein and caloric intake required for individualised care
  2. In patients with caloric or nutrition deficit, consider nutritional supplementation
  3. Discuss multivitamin and mineral needs for the patient with the physician if needed, and administer as per physician’s orders

Further Considerations

  • Is there enough pressure ulcer relief equipment available for high-risk patients?
  • Are nursing assessments carried out as per recommendation to avoid the development of pressure ulcers?
  • Are nurses providing patient centered care so as to avoid development of pressure ulcers and unnecessary complications in wound care?
  • Is enough education on the prevention of pressure ulcers to health care providers, patients and their families, and caregivers, being provided?

Kennedy Terminal Injury

A kennedy terminal injury is a pressure injury which at times tends to develop in individuals who are dying.

These types of pressure injuries start out larger and more superficial than other pressure ulcers, yet develop rapidly in size, depth and colour. In other words, a patient may have no sign of an ulcer in the morning, yet by the afternoon, a dark flat blister would have appeared. Usually, a patient exhibiting a kennedy terminal injury tends to have a life expectancy of between 8 and 24 hours.

Retrieved from https://docplayer.net/21304136-Pressure-ulcers-risk-management-and-treatment.html on 28th June 2022

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Wound Care In Nursing Practice

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The skin is an organ responsible for many of the body’s reactions to the environment, such as protection, temperature control and sensory information. It provides non-verbal information on one’s condition. It also has a profound effect on the psychological well-being of the individual. But like every other organ, it needs to be well cared for to provide optimum functionality. Wound care in nursing practice requires the knowledge of various techniques used in the assessment, treatment and care of the patient with one or multiple wounds. Techniques include debridement, cleaning, bandaging, as well as liaising with the multi-disciplinary team for better and quicker treatment.

Optimum wound care requires:

  • Good relevant patient history taking
  • Detailed documentation
  • Identification of the patients requiring a multidisciplinary approach
  • Early complication detection and referral to the appropriate specialists
  • Patient education
  • Awareness on the psychosocial impact that the skin has on the individual

Wound Healing Process

A wound is the discontinuity of the skin, mucous membrane or tissue caused by physical, chemical or biological insult. Wound healing requires:

  1. The replacement of injured tissue with new tissues
  2. An increased consumption of energy
wound care in nursing practice
Distinct and overlapping phases of wound healing – Retrieved from https://parjournal.net/article/view/1211 on 26th October 2021

HAEMOSTASIS – The body aims to stop the bleeding through vasoconstriction, platelet formation, etc. In other words, haemostasis is the body’s natural physiological response for the prevention and stopping of bleeding.

REMODELLISATION – Takes up to around 2 years of healing. This is why a visibly healed wound can just open by itself, even if untouched. Some ‘simple’ dry skin can trigger a wound to re-open.

Moist Wound Healing in Wound Care

In moist occlusive and semi-occlusive environments, epithelialisation happens at twice the rate when compared to dry environments. Moist wound healing can be achieved through the use of advanced wound care dressings. However, a wet environment can be detrimental to wound care, as this may lead to maceration as well as tissue breakdown. The key to wound healing is to keep the wound bed balanced between dry and wet – find moisture balance!

NOTE: Iodine-impregnated dressings and silver dressings can be used if wound exudate is present. Alginates, which are made of seaweed extract, can absorb exudate. Aquacel AG has the ability to absorb up to 3 times more than alginates.

NOTE: Moist wound healing shouldn’t be used for necrotic digits (fingers and toes) due to ischaemia and/or neuropathy. Necrotic digits should be kept thoroughly dry. If kept wet, infection may travel up through the whole leg, leading to the amputation of not just one toe but a whole foot.

wound care in nursing practice
Retrieved from https://www.slideshare.net/sungwooks/wound-care-59702625 on 26th October 2021

Acute VS Chronic Wounds – chronic wounds happen when things go wrong. This usually happens within the inflammatory phase of wound healing (hours to days following wound infliction).

wound care in nursing practice
Retrieved from https://www.slideshare.net/sungwooks/wound-care-59702625 on 26th October 2021

Problem Wounds – These are wounds that don’t heal due to other local issues, such as infections, individuals on steroidal drugs, immunocompromised individuals, etc.

wound care in nursing practice
Retrieved from https://www.slideshare.net/sungwooks/wound-care-59702625 on 26th October 2021

Local Factors Affecting Wound Healing

Wound healing can be delayed by various factors local to the wound itself. Such factors include:

  • local infection
  • necrotic tissue or foreign body presence
  • poor blood supply / low oxygen perfusion
  • venous stasis – loss of proper vein function of the legs that would normally carry blood back towards the heart
  • lymph stasis – lymph circulation disorder that leads to oedema
  • tissue tension – a state of equilibrium between tissues and cells that prevents over-action of any part
  • haematoma and dead space
  • large defect or poor opposition
  • recurrent trauma
  • x-ray irradiated area
  • wound location – eg. wound over joint

Complications of Wound Healing

  • Infection – red, swollen, painful wound with discharge, pus or bad smell
wound care in nursing practice
Retrieved from https://www.sciencephoto.com/media/108432/view/infected-wound-of-the-thumb on 26th October 2021
  • Avoidable scar
wound care in nursing practice
Retrieved from https://the-medical-negligence-experts.co.uk/claim-types/scarring-negligence/ on 26th October 2021
  • Excess healing-keloid and hypertrophic scar
wound care in nursing practice
Retrieved from https://psderm.com/keloids/ on 26th October 2021
  • Skin pigmentation
wound care in nursing practice
Retrieved from https://dermnetnz.org/topics/postinflammatory-hyperpigmentation on 26th October 2021
  • Marjolin ulcer-occurs due to scar tissue
Retrieved from https://en.wikipedia.org/wiki/Marjolin%27s_ulcer on 26th October 2021
  • Contractures
Retrieved from https://www.saebo.com/contracture/ on 26th October 2021
  • Incisional hernia and wound dehiscence
Retrieved from https://www.woundsource.com/patientcondition/surgical-woundshttps://www.woundsource.com/patientcondition/surgical-wounds on 26th October 2021

Wound Descriptive Terms for Wound Care

  • Necrotic Eschar
Retrieved from https://www.woundsource.com/blog/knowing-difference-between-scabs-and-eschar on 26th October 2021
  • Necrotic Slough
Retrieved from https://www.researchgate.net/figure/Necrotic-skin-covered-with-slough-and-pus-exposing-underlying-fascia-case-number-1_fig2_23560895 on 26th October 2021
  • Infective
wound care in nursing practice
Retrieved from https://www.sciencephoto.com/media/108432/view/infected-wound-of-the-thumb on 26th October 2021
  • Granulation
Retrieved from https://www.woundsource.com/blog/getting-know-granulation-tissue-and-what-it-means-wound-care on 26th October 2021
  • Hyper-granulation
Retrieved from https://sanaramedtech.com/blog/how-to-identify-treat-hypergranulation-tissue/ on 26th October 2021
  • Poor quality granulation
Retrieved from https://www.researchgate.net/figure/Macroscopically-visible-poor-granulation-and-signs-of-infection-observed-on-the-9-th_fig1_256118693 on 26th October 2021
  • Epithelialisation
Retrieved from http://www.plasmamedicalsystems.com/2/medical/clinical-treatment-examples/treatment-of-a-surgical-site-infection-with-plasma-one/ on 26th October 2021
  • Maceration
Retrieved from https://www.healthline.com/health/macerated-skin on 26th October 2021
Retrieved from https://slideplayer.com/slide/12696492/ on 26th October 2021

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Skin Care In Nursing Practice

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Skin care in nursing practice is very important, especially since the skin is responsible for protection, sensation, heat regulation, excretion, secretion and absorption.

  • Protection – from wear and tear (subcutaneous fat beneath the skin acts as a shock absorber and helps to protect the body from trauma); against infection and chemicals (microorganisms cannot breach the barrier created by intact healthy skin); against UV radiation (melanin absorbs UV light and prevents it from damaging cellular DNA);
  • Sensation – the skin is the body’s largest sensory organ. Its nerve receptors detect a number of different stimuli, including mechanical (eg. pressure) and thermal (heat or cold);
  • Heat Regulation – the hypothalamus (found within the brain), which contains the temperature regulating centre, can trigger changes within the skin in response to temperature changes;
  • Excretion – the skin excretes Carbon Dioxide, water, and sweat along with a number of waste products such as Sodium Chloride and Urea;
  • Secretion – Sebacious glands (outgrowths of hair follicles) within the dermis secrete sebum, making the skin water-resistant;
  • Absorption – the skin is a useful absorbent medium for medicines such as hormones and glyceryl trinitrate (for angina treatment), as well as for the application of topical medications aimed to treat skin diseases.

Skin, including intact skin, requires ongoing care. It needs to be kept clean, moisturised and free from infection, and this can be achieved through the use of emollient (moisturiser) therapy.

Moisturisers

Moisturisers come in the form of creams, lotions and ointments. The greasier they are, the better they are at rehydrating the skin.

Moisturiser Creams

Moisturiser creams are a mixture of oil and water, but they require stabilisers (chemicals) to prevent the cream from become contaminated by bacteria and fungi. Chemicals pose a risk for irritations. The upside to moisturiser creams is that they rub easily into the skin without leaving greasy traces.

NOTE: Always test moisturiser creams on a small area eg. on the patient’s back for a minimum of 48 hours – any persistent redness signals allergic reaction.

Moisturiser Lotions

Moisturiser lotions are liquid creams which tend to have a cooling effect on the skin. Whilst moisturiser lotions tend to be less effective at moisturising the skin than creams and ointments, they are considered to be a good choice for normal routine skincare.

NOTE: Moisturiser lotions contain preservatives/chemicals. Test lotions on a small area for a minimum of 48 hours – any persistent redness signals allergic reaction.

Moisturiser Ointments

Moisturiser ointments are oil-based, with the main ingredient usually being white soft paraffin, containing very little water. This makes ointments very greasy and messy. However, ointments are more effective than creams, and are ideal for very dry and inflamed skin especially when applied during night time. Ointments form a layer on the skin that prevents water loss, while providing further hydration to the skin.

NOTE: Ointments are unlikely to cause adverse reactions since preservatives are not needed as bacteria and fungi cannot grow within this medium.

Applying Moisturisers

  1. Wash skin (see bathing section below).
  2. Dry carefully by patting – DO NOT rub vigorously as doing so will damage delicate and dry skin, as well as aggravate itchy skin.
  3. Apply moisturiser immediately after while skin is warm and at its most receptive state. Start from the top and work downwards using downward strokes parallel to the direction of the hair follicles’ growth…this will prevent hair follicles from becoming blocked, leading to folliculitis (inflamed or infected follicles).

Bathing

Evaporation of water from the epidermis causes skin tightening, leading to dry skin. Hospital ambience, including the hot dry conditions and high temperature and chemical use on bed sheets, increases risk for dry skin.

DO…

  • MOISTURISE the patient’s skin to reduce water loss (the surface film created by moisturisers help slow down water loss)
  • ADD BATH OIL such as Oilatum, E45 Wash, or Aqueous Cream to the water, instead of soap, to promote rehydration of the skin due to the increased oil-to-water ratio (attn. patient safety – oils make baths slippery!)

DO NOT…

  • Do not use soap on dry skin as soap worsens the problem since it removes the skin’s natural oils, increasing dehydration
  • Do not over-wash the skin as this removes natural oils and commensal (harmless) bacteria that helps in the prevention of pathogen growth

The Scalp

The scalp is prone to becoming dry. Patients with a dry scalp usually respond well to appropriate shampoos which usually contain coal tar (eg. Polytar and T-Gel). Such shampoos need to be used on alternate days.

In case of irritation, a milder form of shampoo should be used. If dry scalp persists apply coconut oil at night.

Infections

Human skin is covered in commensal (harmless) bacteria and fungi. When the balance of commensal organisms is disrupted or when the skin integrity is breached, organisms penetrate the skin’s protective surface, resulting in cutaneous infections.

Skin Care In Nursing Practice
Retrieved from https://quizlet.com/402852754/microbiology-infectious- diseases-immunology-and-toxicology-flash-cards/ on 22nd October 2021

Bacteria

Bacteria can multiply quickly at body temperature, reaching harmful levels very fast. MRSA (Meticillin-Resistant Staphylococcus Aureus) and C.Diff (Clostridium Difficile) are two examples of such harmful bacteria.

Skin bacterial infections are most commonly caused by Staphylococcal and Streptococcal bacteria (eg. Impetigo and Folliculitis). These are more prominent in low hygienic conditions and in hot and wet climates. Such infections can be treated with a combination of antibiotics and good hygiene. Although superficial bacterial infections may respond to topical antibiotic treatment, oral antibiotics may be required for complete treatment. Additionally, topical antibiotics may also cause allergies, thus should be used with caution. NOTE: skin bacterial infections may be avoided by maintaining good hygiene and not itching.

Fungi

Fungi are organisms that live on both living and dead hosts.

Types of Fungal Infections include:

Tinea (Ringworm) can affect the body or the scalp. It is easily spread amongst children, and is often passed on from animals.

Candidiasis (Yeast) is usually found within skin folds following instances in which the skin is left wet. Pregnant women, the immuno-compromised, individuals on a broad spectrum of antibiotics, diabetics and HIV-positive individuals are more prone to getting Candidiasis.

Treatment for superficial fungal infections (eg. Tinea and Candidiasis) respond well to topical anti-fungal treatment, which should be applied diligently for the recommended time to avoid re-infection. Candida infection beneath the nail bed requires oral anti-fungal treatment, as topical treatment is unable to penetrate effectively in this case.

NOTE: Fungal infections can be avoided through proper skin care, including extra attention to skin folds with regards to washing and drying.

Parasites

Parasites are organisms that live on or within a host such as an animal or plant, getting food from the same host. Scabies, caused by mites, burrow into the skin, resulting in severe itching.

Viral Infections

Herpes Zoster (Shingles), a viral infection which is caused by the Varicella Zoster Virus (Chickenpox), is most commonly seen in individuals over 40 years of age. It causes pain which at times may be suicidal.

Herpes Simplex (causes Herpes), another viral infection, can be found in almost the whole adult population, although it may not produce visible symptoms.

Human Papilloma Virus (Warts) can affect people of all ages.

TREATMENT:

Herpes Simplex and Herpes Zoster are most commonly treated by Acyclovir, an antiviral treatment which can be used either topically or orally. Warts are usually removed with over-the-counter treatments containing salisylic acid, which basically burns away the thickened hard skin. Common warts may also be removed with Cryotherapy through the use of liquid nitrogen.

Infestations

When living creatures invade the body, an infestation occurs. Such living creatures may be seen miroscopically, and include mites (Scabies: see further up) and lice.


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Skin Lesions

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Skin lesions can be defined as a part of the skin that has an abnormal growth or appearance when compared to intact skin. Skin lesions can be classified into 4 types:

  1. Infections
  2. Allergies
  3. Burns
  4. Skin Cancer

1. Skin Lesions – Infections

Athlete’s Foot

skin lesions athlete's foot
Retrieved from https://health.clevelandclinic.org/how-you-can-stop-foot-and-toe-fungus-in-its-tracks/ on 15th October 2021

Athlete’s foot presents as itchy red peeling in the skin between the toes as a result of infection by the fungus tinea pedis. Athlete’s foot is common due to the said areas being prone to sweat or when left wet/ not thoroughly dried.

Candidiasis

skin lesions candidiasis
Retrieved from https://www.mymed.com/diseases-conditions/candida/signs-and-symptoms-of-candidiasis on 15th October 2021

Candidiasis is a fungal infection caused by Candida (a yeast). Candida usually presents on the skin and/or within the body, in areas such as the mouth, throat, gut, vagina, as well as areas prone to sweat (eg. under the breasts) and wetness (eg. nappy rash following prolonged humid environment).

When presenting in the mouth, Candidiasis (also known as Thrush) is characterized by white discolorations in the tongue, around the mouth, and the throat. Sometimes, irritation that causes discomfort when swallowing may occur. Oral Candidiasis can at times be caused in prolonged use of oral steroid medication eg. in asthmatic patients.

When presenting within the skin, Candidiasis causes itching, irritation, chafing or broken skin.

Ringworm

skin lesions ringworm
Retrieved from https://www.askdrsears.com/topics/health-concerns/skin-care/ringworm/ on 15th October 2021

Ringworm, a fungal infection of the skin, can affect both humans and animals. Typically, humans acquire ringworm from strays or pets. Ringworm usually presents in areas on the skin such as on the scalp, feet, groin and beard.

Mild ringworm is usually treated successfully by antifungal topical medication (cream). However, more severe ringworm infection usually requires antifungal oral medication to be successfully treated.

Boils and Carbuncles

skin lesions boils and carbuncles
Boil (left) vs Carbuncles (right) – Retrieved from https://www.diagnose-me.com/symptoms-of/boils-abscesses-carbuncles.php on 15th October 2021

Boils and Carbuncles are classified as bacterial infections. They happen as a result of inflammation of the hair follicles and sebaceous glands, and quite commonly present on the dorsal neck. Usually, local antibacterial topical medications (eg. Fucidin) don’t work on boils and carbuncles – they are usually treated through oral antibiotics.

Impetigo

skin lesions impetigo
Retrieved from https://www.nhs.uk/conditions/impetigo/ on 15th October 2021

Impetigo is a bacterial (staphylococcus) infection of the skin, commonly found in young children. It is highly contagious – in fact, children with Impetigo are required to be kept home so as to avoid spreading of the infection. Impetigo is commonly found around the mouth and nose, and presents as pink water-filled raised lesions which turn into a yellowish crust, which eventually ruptures.

Cold Sores

skin lesions cold sores
Retrieved from https://www.evansondds.com/cold-sores-what-are-they-how-to-avoid-them/ on 15th October 2021

Cold sores are small fluid-filled blisters presenting around the lips and in the oral mucosa, that cause itching and a stinging sensation. They are caused by Herpes Simplex infection. Herpes Simplex is a lifelong virus that once acquired remains dormant for long periods of time until it causes an outbreak following a trigger.

Chickenpox

skin lesions chickenpox
Retrieved from https://www.healthychildren.org/English/safety-prevention/immunizations/Pages/Chickenpox-Vaccine-What-You-Need-to-Know.aspx on 15th October 2021

Chickenpox is caused by the Varicella Zoster virus. It presents as a very itchy skin rash with blisters. The Varicella Zoster virus is a lifelong virus that once acquired stays in the body, specifically in the sensory nerve ganglia, as a dormant infection.

Shingles

skin lesions shingles
Retrieved from https://www.straitstimes.com/singapore/health/5-things-to-know-about-shingles on 16th October 2021

Shingles is the reactivation of the Varicella Zoster virus (which initially causes Chickenpox). Typically, Shingles causes pain in a particular area in the body, which is later on followed by a rash, which initially appears as red spots before turning into blisters that eventually dry up and form scabs.

Warts

skin lesions warts
Retrieved from https://www.skincarenetwork.co.uk/dermatology/men/genital-warts/ on 16th October 2021

Warts are a type of skin infection resulting from the Human Papillomavirus (HPV). Warts present as rough, skin-coloured bumps on the skin which are highly contageous and can be easily spread through skin-to-skin contact. There is currently a vaccine which is offered to girls aged 12 years (ideally administered prior to 1st sexual encounter) to prevent development of the HPV.

2. Skin Lesions – Allergies

Contact Dermatitis

skin lesions contact dermatitis
Retrieved from https://nationaleczema.org/eczema/types-of-eczema/contact-dermatitis/ on 16th October 2021

Contact Dermatitis is caused by the irritation or inflammation of the skin following direct contact with a substance or material that triggers an allergic reaction. It causes itching, redness as well as swelling of the skin which eventually progresses to blistering.

Psoriasis

skin lesions psoriasis
Retrieved from https://infusionassociates.com/infusion-therapy/psoriasis/ on 16th October 2021

Psoriasis is a chronic condition whereby overproduction of skin cells occurs. It presents as reddened epidermal lesions covered by dry silvery scales, and is commonly triggered by trauma, infection, hormonal changes and stress.

3. Skin Lesions – Burns

skin lesions burns
Retrieved from https://urgentcaresouthaven.com/burn-care-at-home-the-dos-and-donts-to-keep-in-mind/ on 16th October 2021

Burns are tissue damage and cell death that result from heat, UV radiation, chemicals or electricity. Burns can be minor medical problems or life-threatening emergencies, and treatment depends on their location and severity.

Life-threatening problems happen since in burns:

  1. the body loses fluids, causing dehydration and electrolyte imbalance, which may lead to circulatory shock;
  2. the burned skin is only sterile for 24 hours, after which the resulting wound becomes prone to infection.
degrees of burns
Retrieved from https://pt.slideshare.net/winreyes/burn-injury-13545329/3 on 16th October 2021

Estimating the extent of burns in percentages using the rule of nines…

Following calculation of the extent of burns in a patient, a patient is considered critical if:

  • >25% of the body has 2nd degree burns
  • >10% of the body has 3rd degree burns
  • 3rd degree burns are present on the face, hands or feet
estimating burns rule of nines
Retrieved from https://www.chegg.com/homework-help/human-anatomy-8th-edition-chapter-5-problem-6cr-solution-9780134243818 on 16th October 2021

4. Skin Lesions – Skin Cancer

There are 3 major types of skin cancer:

  • Basal Cell Carcinoma
  • Squamous Cell Carcinoma
  • Malignant Melanoma

Basal Cell Carcinoma

Basal Cell Carcinoma is the least malignant but most common type of skin cancer that most often develops on areas of skin exposed to the sun. This type of cancer arises from cells within the stratum basale and presents itself as shiny dome-shaped nodules which eventually develop a central ulcer.

Squamous Cell Carcinoma

Squamous Cell Carcinoma is the second most common form of skin cancer which is characterised by abnormal accelerated growth of squamous cells. Squamous Cell Carcinoma arises from cells within the stratum spinosum and presents itself as a scaly, reddened papule that gradually forms a shallow ulcer with a firm raised border.

Malignant Melanoma

skin lesions malignant melanomas
Retrieved from https://www.medpagetoday.com/resource-centers/advances-hematologic-malignancies/noncutaneous-second-primary-malignancy-patients-melanoma/2864 on 16th October 2021

Malignant Melanoma, the most deadly form of skin cancer, develops from the pigment-producing cells known as melanocytes. It may develop spontaneously or from existing moles that suddenly start exhibiting changes, indicating cancer growth.

skin lesions malignant melanomas
Retrieved from https://miiskin.com/melanoma/symptoms-signs/ on 16th October 2021

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The Integument – Skin Anatomy and Physiology

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The skin, which is otherwise referred to as the cutaneous membrane or the integument, is a pliable (can stretch) yet adaptable external body covering. It is a dry membrane (when intact) that acts as a barrier for water – it keeps water and important molecules within the body, whilst keeping water from outside sources out of it.

Functions of the Integument

The integument acts as protection against:

Mechanical Damage

  • Through Keratin, which is a protein, the skin offers protection from mechanical damage which includes direct hits;
  • Pressure receptors act as sensors that sense extra pressure on the skin (eg. a patient who is immobile cannot automatically retract when pressure receptors sense prolonged pressure on the skin, and this results in bed sores);

Chemical Damage

  • Impermeability to chemical substances that can cause damage to deeper tissues is caused by the keratinized cells within the integument;
  • Water-diluted chemicals trigger pain receptors when in contact with the skin;

Bacterial Damage

  • In normal circumstances, skin secretions, which are acidic, inhibit bacteria;
  • Intact skin provides an ‘unbroken surface‘;
  • Phagocytes within the dermis ingest foreign pathogens (fights off bacteria), stopping them from damaging structures within the integument;

UV Radiation

  • In normal circumstances, Melanin, which is produced by melanocytes, offers protection from UV radiation, but if amount of UV damage is higher than the produced amount of Melanin, damage is caused;

Thermal Damage

  • Changes within the environment trigger a response by heat or cold pain receptors to avoid thermal damage to be caused to the skin

Desiccation

  • Desiccation (extreme dryness of the skin) is prevented through Keratin and Glycolipids, both of which are hydrophobic i.e. waterproof

Heat Loss or Heat Retention

  • In the case of heat retention, sweat glands activate, causing blood to rush to the skin capillary beds so heat is lost. The process occurs in reverse in the case of heat loss;

Urea and Uric Acid

  • Sweat glands secrete urea and uric acid, both of which are broken down protein, through perspiration;

Modified Cholesterol Molecules

  • Vitamin D is important for the body’s wellbeing. Sunlight causes modified cholesterol molecules to convert to Vitamin D;
integument
Retrieved from https://www.austincc.edu/apreview/PhysText/Integument.html on 13th October 2021

Structure of the Integument

The EPIDERMIS contains no blood vessels. It gets its needed nutrients and blood supply from the dermis.

The DERMIS contains larger vasculature structures within its lower part.

The HYPODERMIS, which is mostly adipose tissue, connects the skin to underlying organs, acts as a shock absorber, and provides insulation of the deeper tissues from extreme thermal changes coming from the body’s outside environment.

Histology

The Epidermis consists of the following layers:

integument
Retrieved from https://www.pinterest.com/pin/675540012830455280/ on 13th October 2021
  1. Stratum Corneum – 20 -30 layers of anucleated cells thick, impregnated with Keratin; allows top layer loss and is subject to wear and tear; cells are replaced by those produced through division of the deeper Stratum Basale cells.
  2. Stratum Lucidum – flatter cells that start to fill up with Keratin, which end up dying and forming the clear Stratum Lucidum in the process.
  3. Stratum Granulosum & Stratum Spinosum – daughter cells of the Stratum Basale push themselves upwards towards the skin surface, i.e. within these two layers.
  4. Stratum Basale – deepest layer of the epidermis; contain Keratinocytes (which undergo continuous cell division), Melanocytes (containing Melanin) and Tactile cells.

The Dermis consists of the following layers:

integument
Retrieved from https://www.semanticscholar.org/paper/Fibroblast-heterogeneity%3A-more-than-skin-deep-Sorrell-Caplan/db56d29471a1dd4867dd142a45d7e8acd2e7803e/figure/2 on 13th October 2021
  1. Papillary Layer – the upper dermal region which is made up of areolar connective tissue; contains dermal papillae (finger-like projections) which indent the epidermis above it.
  2. Dermal Papillae – contain Capillary Loops which provide nutrients to the epidermis, Pain Receptors which are free nerve endings, and Touch Receptors (a.k.a. Meissner’s Corpuscles).
  3. Reticular Layer – deepest, thickest layer of the skin which contains irregularly arranged dense fibrous connective tissue, sweat and oil glands, Phagocytes, blood vessels (at the base, just above the Hypodermis), and Pacinian Corpuscles (deep pressure receptors which react to different pressures on the skin).

Skin Colour

The major contributor to the colour of the skin is Melanin – to be exact, the amount and kind of Melanin (yellow, reddish, brown or black) found within the Epidermis. Additionally, Melanin protects the skin from UV radiation.

Other contributors to skin colour include Carotene (deposited in the Stratum Corneum and subcutaneous tissue) and Oxygen-rich Haemoglobin within the blood vessels in the Dermis (contribute to pinkish/reddish colour in the skin).

Skin Appendages

Skin appendages are structures associated with the skin that carry out particular functions such as sensations, heat loss, contractility and lubrication. These structures, which include cutaneous glands, hair and hair follicles, and nails, rise from the epidermis but originate from the dermis.

Cutaneous Glands:

Retrieved from https://europepmc.org/article/med/31608304 on 14th October 2021
  • are all exocrine glands
  • are formed by cells within the stratum basale, pushing into deeper skin regions, but mostly reside within the dermis
  • can be divided into 2 types: Sebaceous Glands (related to hair and hair follicles that exert sebum) and Sweat Glands

SEBACEOUS GLANDS

  • are found everywhere on the skin except on the palms of the hands and the soles of the feet
  • produce sebum – a combination of oily substances and fragmented cells which lubricates the skin, keeping it soft and moist, prevents hair from becoming brittle and also kills bacteria through chemicals contained within (note: blocked sebaceous gland duct results in a whitehead; oxidised and dried accumulated material forms into a blackhead)
  • usually empty into hair follicles, but at times may open directly onto the surface of the skin

SWEAT GLANDS

  • are found everywhere within the skin
  • include 2 types: Eccrine Glands (widely spread throughout the body – produce sweat and contribute towards the body’s heat-regulating system) and Apocrine Glands (larger than eccrine glands – found in the axillary and genital area – are activated during puberty through androgen hormones – produce odor)
  • sweat produced is a clear acidic (pH4-6) secretion that inhibits bacterial growth – sweat is a combination of water, salts (especially sodium chloride), vitamin C, traces of metabolic wastes (ammonia urea and uric acid) and lactic acid (causes a decrease in BP through excessive sweating)
Retrieved from https://pediaa.com/difference-between-sebaceous-glands-and-sweat-glands/ on 14th October 2021

Hair and Nails

Hair:

  • is a flexible epithelial structure
  • is formed by the stratum basale epithelial cells within the hair bulb matrix
  • shaft is made of dead material, almost entirely protein
  • structure includes the ROOT (the part enclosed in the follicle) and the SHAFT (the part projecting out of the scalp or skin surface)
  • consists of the medulla, cortex layer, and cuticle (keeps each hair apart from another, provides strength to the inner hair layers to keep them compacted, but is exposed to wear and tear)
  • include the Arrector Pili, which are small bands of smooth muscle cells that connect each side of the hair follicle to the dermal tissue – when these muscles contract, hair is pulled upright, resulting in goose bumps on the skin surface
Retrieved from https://rejuvenatehairtransplant.com/blog/hair-structure/ on 14th October 2021

Nails:

  • can be seen as a modification of the epidermis
  • have a free edge, a body and a root
  • have borders which are overlapped by skin folds known as nail folds
  • have cuticles which aim to offer protection from pathogens (removal of the cuticle exposes the skin to pathogens, which makes the skin susceptible to fungal infections

NOTE: Creams don’t penetrate into the nail bed easily, which is why the best treatment for nail fungus is oral therapy.

Retrieved from https://www.informedhealth.org/structure-of-the-nails.html on 14th October 2021

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Becoming Leaders In Nursing Care

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As nursing students we gain knowledge through informative lectures in all clinical aspects related to nursing. But our ultimate aim as future nurses should be to develop the ability to embed all gained knowledge into our daily nursing practice by providing patient-centered care. As good future nurses we need to keep up-to-date with innovative evidence-based nursing practices and be prepared to challenge the status quo whilst backing up our rationales with relevant literature. This is what we, as future nurses, need to do to become leaders in nursing care.

4 Primary Domains in Nursing

Retrieved from https://nurseslabs.com/nursing-theories/ on 22nd January 2022
Retrieved from https://nurseslabs.com/nursing-theories/ on 22nd January 2022

The Nursing Process

leaders in nursing care
Retrieved from https://nurseslabs.com/nursing-diagnosis/ on 7th November 2021
Retrieved from https://www.pinterest.ph/pin/611222980657579285/ on 7th November 2021
Retrieved from https://www.pinterest.com/pin/732679433111887637/ on 7th November 2021

Holistic Patient Care Considerations

leaders in nursing care
Retrieved from https://www.thepurpose.co/about on 7th November 2021

The Roper Logan Model of Activities of Daily Living

becoming leaders in nursing care activities of daily living
Retrieved from https://nursinganswers.net/reflective-guides/roper-logan-tierney.php on 12th October 2021

The Roper Logan model of activities of living, based on Nancy Roper’s 1976 work, was initially developed in 1980. The model, which is set on the 12 activities of living needed to live, acts as an assessment tool for nurses to assess a patient’s independence and/or potential for independence in relation to daily living activities. This model ranges from complete dependence to complete independence, and helps in pointing out required interventions and support to increase patient independence.

8 Dimensions of Patient-Centered Care

leaders in nursing care
Retrieved from https://www.researchgate.net/figure/Eight-dimensions-of-Pickers-Patient-centred-Care_fig1_322011083 on 12th October 2021

Elderly Care

When caring for the elderly, nurses should provide:

  • Proper nutrition and hydration
  • Incontinence prevention or management
  • Mobility maintenance – encourage mobility wherever possible
  • Medication management – assess needs and aim to reduce polypharmacy
  • Skin and foot care
  • Patient safety – prevent accidents/falls
  • Memory loss assessment

Becoming Leaders in Nursing Care through the 6Cs

leaders in nursing care
Retrieved from https://www.pinterest.co.uk/pin/462041243005083458/ on 13th October 2021

The 6Cs provide:

  • a foundation on which nursing care should be built on
  • guidance for nurses who aim to become leaders in nursing care by leading towards changes for the better within the profession
  • added value in the daily nursing practice that equals to better outcomes, better experiences and better use of resources

As leaders in nursing care, nurses should:

  • focus on promoting preventative measures, which improve the patient’s health, avoids unnecessary complications and lessens the burden of increased workload
  • promote patient-centered care whilst keeping up to date with innovative methods and technology use that increase quality and safety within the provided care
  • aim for efficiency to prevent resource shortage which hinders the quality and progress of the care given to the patient

This can only be achieved through:

Nursing Care:

Nurses should practice good communication skills with the patients, treating them as individuals rather than just a bed number;

Nurses should practice good communication skills within the multi-disciplinary team as this provides holistic care to the patient;

Nurses should focus on providing good, detailed documentation to ensure optimum patient care;

Nurses should not hold back from taking initiative and be part of the doctors’ ward rounds – patient observations are made by the nurse throughout the time spent with the patient, and so, the nurse plays an important role in individualised patient care;

Professional Development:

Nurses should aim to improve their nursing knowledge and work on skill development;

Nurses increase their knowledge through the experience they gain whilst working towards the wellbeing of their patients;

Nurses should be aware of different policies related to the different organisations;

Nurses should not be afraid to challenge current practices whilst backing up their theories with evidence;

Nurses should be active in nursing-related issues and act professionally – through their presence and actions, nurses are representing the nursing profession.


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Total Parenteral Nutrition – Indications & Complications & Nursing Care

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Total parenteral nutrition can provide an individual with the necessary nutritional support and provision of therapeutic nutrients to maintain or restore optimal nutrition status and health. Total Parenteral Nutrition bypasses the digestive system by dripping a nutritionally adequate hypertonic solution containing glucose, protein, hydrolysates, minerals and vitramins directly into the venous system through an indwelling catheter into the superior vena cava or another main vein.

Total Parenteral Nutrition Contents

MACRO-NUTRIENTS:

  • Carbohydrates (glucose)
  • Proteins (amino acids)
  • Lipids (fatty acids)

OTHERS:

  • Electrolytes
total parenteral nutrition
TPN Bag consisting of Macro-Nutrients + Electrolytes – Retrieved from https://www.mims.com/hongkong/drug/info/olimel%20n9e-periolimel%20n4e?type=full on 2nd June 2021

MICRO-NUTRIENTS:

  • Multi-Vitamins (eg. Vitamin B)
  • Trace Elements/Minerals (eg. Selenium & Manganese)

A bag of TPN provides the patient with about 2270kcal nutritional intake. This high calorie intake is not considered to be too much since patients on TPN are usually fighting inflammation, requiring wound healing etc.

Indications for Total Parenteral Nutrition

Total Parenteral Nutrition is indicated for patients who:

  • are lacking nutritional requirements (commonly related to health-related conditions)
  • have documented inadequate oral intake (common indication in the elderly)
  • experience an unpredictable return of their GI function (eg. malabsorption leading to lack of good nutritional outcome)
  • are on a prolonged nil-by-mouth period (eg. patients undergoing GI surgery)

DIGESTIVE DISORDERS:

  • GI fistulae
  • major GI surgery
  • uncontrolled malabsorption (eg. in Chron’s Disease)
  • short bowel syndrome (gastroschisis, volvulus & necrotising enterocolitis)
  • severe enteropathy (genetic-related issues such as microvillus atrophy, tufting enteropathy, congenital, auto-immune)
  • dysmotility or pseudo-obstruction
  • severe acute pancreatitis

NON-DIGESTIVE DISORDERS:

  • post-chemotherapy
  • radiotherapy
  • severe mucositis
  • bone marrow transplant
  • multi-organ failure in extensive trauma and burns
  • immature gut

Contraindications for Total Parenteral Nutrition

  • functioning GI tract (if the problem is with the upper GI tract and the lower GI tract is fully functioning, enteral feeding directly into the jenunum would be recommended)
  • need for <5 days of TPN with no severe malnutrition
  • difficulty in obtaining venous access
  • poor prognosis that doesn’t warrant aggressive nutritional support
  • if risks outweigh the benefits

TPN and CVCs Complications

  • catheter and systemic infections
  • catheter obstruction eg. blocked lumens
  • pneumothorax (may happen during catheter insertion)
  • thrombosis (may happen during catheter insertion)
  • bone disease
  • hepatobiliary disease (eg. TPN-induced liver failure due to the nutritional infusion being administered directly into the venous system)
  • renal disease

Patient Monitoring

  • vital signs (temperature to monitor for sepsis; blood glucose monitoring due to TPN containing 40% glucose)
  • intake & output
  • weight (especially malnourished patients)
  • fluid requirements
  • patient complaints
  • CVC exit site (monitor for signs of inflammation)
  • overall clinical status
  • blood (renal: U&E, Mg, Ca, Phos, Cr; heamat: CBC, INR; liver function: Alk Phos, Bil.; Glucose and Lipid, Iron and Ferritin; Albumin)
  • MRSA nasal swabbing (if patient is colonised with MRSA, treatment is required prior to developing into an infection)

TPN Bag Changing Technique

  1. use an aseptic non-touch technique
  2. hand hygiene
  3. don apron
  4. clean work surface with 70% alcohol and let dry
  5. cover with sterile drape
  6. place all sterile items on it: sterile IVI tubing, syringe and needle
  7. other needed items should be placed in a cleaned tray
  8. apply alcohol handrub
  9. don gloves
  10. switch off volumetric pump
  11. disconnect previous TPN line from the needleless valve attached to the central venous catheter
  12. mix the 3 compartments of the new TPN bag and hang on drip stand – DO NOT TOUCH CONNECTION PARTS
  13. disinfect the needleless valve with 2% chlorhexidine in 70% alcohol and leave to dry
  14. spike TPN bag with infusion line and prime whilst still capped
  15. remove cap and connect to patient through the needleless valve
  16. add additives Additrace and Cernevit to the TPN bag from the injectable port using an aseptic non-touch technique
  17. dispose of materials appropriately

Below you can find a video that can help provide a more visual approach to total parenteral nutrition.

Total Parenteral Nutrition OSCE

Special thanks to the creators of the featured video on this post, specifically Youtube Channel University of Manitoba Nursing Skills. Featured image credit: https://badgut.org/information-centre/a-z-digestive-topics/parenteral-nutrition/

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Peripheral Vascular Access – Sites, Indications & Contraindications

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Peripheral vascular access is commonly sought through the non-dominant upper extremity due to a reduced risk of dislodgement, thrombosis and thrombophlebitis. However, peripheral venous line cannulation can be done successfully through various sites in the body.

Peripheral Vascular Access Sites

Upper Extremity: The metacarpal veins on the dorsum of the hand drain proximally through the dorsal venous arch into the cephalic and basilic veins in the forearm. These connect by the median cubital and median antebrachial veins in the antecubital fossa region, prior to continuing up the arm.

peripheral vascular access
Retrieved from https://www.nursingtimes.net/clinical-archive/infection-control/vessel-health-and-preservation-2-inserting-a-peripheral-iv-vascular-cannula-01-05-2020/ on 1st June 2021

Lower Extremity: lines may be placed from the dorsal venous plexus of the foot which become the great and small saphenous veins in the leg.

Retrieved from https://www.jaypeedigital.com/book/9789351524229/chapter/ch18 on 1st June 2021
peripheral vascular access
Retrieved from https://www.quora.com/How-do-you-draw-blood-from-veins-in-the-foot-I-cant-find-any-veins-there on 1st June 2021

Scalp: may be appropriate in neonates or infants. Sites include the frontal, occipital, superficial temporal or posterior auricular veins.

peripheral vascular access
Retrieved from https://www.researchgate.net/figure/Simplified-schematic-of-the-arterial-supply-of-the-skull-lateral-view-Vessels_fig2_328171256 on 1st June 2021

Preferred veins for cannulation are straight, distal and non-branched (since venous valves are usually located close to branching points). When accessing a vein, a tourniquet is to be placed proximally to the site to create engorgement in the vein. Vein should feel spongy and should not pulsate on palpation (indication of an artery rather than a vein). Avoid veins that are hard to the touch due to possible thrombosis.

Indications for Peripheral Vascular Access

  • administration of IV medications
  • administration of IV fluids
  • phlebotomy (prior to medication and/or fluids to avoid dilution or contamination of blood samples)

Contraindications for Peripheral Vascular Access

While there are no absolute contraindications for cannulation, there are relative contraindications for which clinical judgement on benefits and risks of procedure is warranted. These include:

  • coagulopathy
  • local infection
  • burns
  • compromised skin at planned insertion site
  • previous lymphatic nodal clearance
  • arteriovenous fistula formation
  • deep vein thrombosis

In the case of extended treatment, it is best to opt for a central venous catheter rather than peripheral vascular access, as this offers lower failure rates in relation to long-term use.

Optimum PVA Outcome

  • prompt placement of peripheral vascular access when required
  • regular monitoring of line function
  • consideration regarding need for venous access
  • removal of lines when no longer indicated
  • early intervention in the case of complications

Below you can find a collection of videos that can help provide a more visual approach to peripheral vascular access.

IV Cannulation OSCE

BD Venflon I IV Cannula

IV Insertion Common Mistakes

Special thanks to the creators of the featured videos on this post, specifically Youtube Channels Geeky Medics, BD and Practical Anesthesia Techniques.

Reference:

Beecham, G.B. & Tackling, G. (2020). Peripheral Line Placement. StatPearls Publishing. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK539795/ on 2nd June 2021


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